4-Fluorophenol
- CAS NO.：371-41-5
- Empirical Formula: C6H5FO
- Molecular Weight: 112.1
- MDL number: MFCD00002316
- EINECS: 206-736-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 14:15:32
What is 4-Fluorophenol?
Chemical properties
white to light yellow crystal powder
The Uses of 4-Fluorophenol
4-Fluorophenol is a fluorinated phenolic compound with various applications as an starting reagent for the synthesis of pharmaceutical goods. It is widely used intermediate in the industrial production of pharmaceuticals cisapride and Sabeluzole from Janssen, Sorbinil from Pfizer, Progabide from Synthelabo.
Definition
ChEBI: 4-fluorophenol is a fluorophenol that is phenol in which the hydrogen para- to the hydroxy group has been replaced by a fluorine. It is a fluorophenol and a member of monofluorobenzenes. It is used as an intermediate in the production of liquid crystals.
Preparation
Acetyl hypofluorite also will fluoro-demetallate benzene derivatives, for example mercury derivatives of phenol gave 4-fluorophenol.
Synthesis Reference(s)
Tetrahedron, 52, p. 23, 1996 DOI: 10.1016/0040-4020(95)00867-8
Hazard
Irritant.
Properties of 4-Fluorophenol
| Melting point: | 43-46 °C (lit.) |
| Boiling point: | 185 °C (lit.) |
| Density | 1.22 |
| Flash point: | 155 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | 80g/l |
| form | Crystalline Solid |
| pka | 9.89(at 25℃) |
| color | Yellow-beige to pink |
| PH | 5.4 (H2O, 20℃)(saturated aqueous solution) |
| Water Solubility | 50 g/L |
| BRN | 1362752 |
| Stability: | Stable. Flammable. Incompatible with strong oxidizing agents. |
| CAS DataBase Reference | 371-41-5(CAS DataBase Reference) |
| NIST Chemistry Reference | Phenol, 4-fluoro-(371-41-5) |
| EPA Substance Registry System | Phenol, 4-fluoro- (371-41-5) |
Safety information for 4-Fluorophenol
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4-Fluorophenol
4-Fluorophenol manufacturer
SOLFYN INTERNATIONAL LLP
1Y
Phone:+91-9321772608
Whatsapp: +91 9321772608
product: Para Fluoro Phenol (PFP) 99%
Aarti Industries Limited (AIL)
1Y
Phone:+91-9920899935
Whatsapp: +91 9920899935
product: 371-41-5 4-Fluorophenol 98%
ALS INDIA LIFE SCIENCES
1Y
Phone:+91-8977036379
Whatsapp: +91 8008166674
product: 4-Fluorophenol 98%
Inventys Research Company Pvt Ltd
1Y
Phone:+919320013358
Whatsapp: +91- 9320013358
product: 4-Fluorophenol 371-41-5 99.93
New Products
Tert-butyl bis(2-chloroethyl)carbamate 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL N-octanoyl benzotriazole 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid DIETHYL AMINOMALONATE HYDROCHLORIDE 1,1’-CARBONYLDIIMIDAZOLE R-2-BENZYLOXY PROPIONIC ACID 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) N-METHYL INDAZOLE-3-CARBOXYLIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5-BROMO-2CYANO PYRIDINE 5,6-Dimethoxyindanone 5-broMo-2-chloro-N-cyclopentylpyriMidin-4-aMine 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 1-(4-(aminomethyl)benzyl)urea hydrochloride 2-aminopropyl benzoate hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
You may like
-
4-Fluorophenol 98%View Details -
4-Fluorophenol 98%View Details
371-41-5 -
4-Fluorophenol pure CAS 371-41-5View Details
371-41-5 -
4-Fluorophenol, GR 99% CAS 371-41-5View Details
371-41-5 -
Para Fluoro Phenol (PFP) 99%View Details
371-41-5 -
4-Fluorophenol 371-41-5 99.93View Details
371-41-5 -
4-Fluorophenol CAS 371-41-5View Details
371-41-5 -
4-Fluorophenol CAS 371-41-5View Details
371-41-5
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.