4-Fluorophenethylamine

CAS NO.：1583-88-6
Empirical Formula: C8H10FN
Molecular Weight: 139.17
MDL number: MFCD00134208
EINECS: 216-435-6
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is 4-Fluorophenethylamine?

Chemical properties

clear colorless to slightly yellow liquid

The Uses of 4-Fluorophenethylamine

4-Fluorophenethylamine may be employed as nucleophile in the synthesis of 2-amino-4-arylpyrimidine derivatives. It is suitable for use in the preparation of ortho-metalated primary phenethylamines having electron-releasing and electron-withdrawing groups on the aromatic ring, leading to complexes containing six membered palladacycles.

What are the applications of Application

4-Fluorophenethylamine is a direct 5-HT agonist

What are the applications of Application

Firstly, ethyl 2-cyano-3,3-dimethythioacrylate was prepared from reactions of ethyl cyanoacetate with carbon disulfide and dimethyl sulfate. Secondly, it reacted with 4-fluorophenethylamine to yield ethyl 2-cyano-3-methythioacrylate-3-[2-(4- fluorophenyl)-ethylamino]-acrylate.

Precautions

Stable under recommended storage conditions. Incompatible with oxidizing agents and acids.

Properties of 4-Fluorophenethylamine

Boiling point:	50-52 °C/0.15 mmHg (lit.)
Density	1.061 g/mL at 25 °C (lit.)
refractive index	n20/D 1.5072(lit.)
Flash point:	174 °F
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
form	Liquid
pka	9.84±0.10(Predicted)
Specific Gravity	1.061
color	Yellow
Water Solubility	Slightly soluble in water.
InChI	InChI=1S/C8H10FN/c9-8-3-1-7(2-4-8)5-6-10/h1-4H,5-6,10H2
CAS DataBase Reference	1583-88-6(CAS DataBase Reference)

Safety information for 4-Fluorophenethylamine

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Skull and Crossbones Acute Toxicity GHS06
GHS Hazard Statements	H227:Flammable liquids H300:Acute toxicity,oral H301:Acute toxicity,oral H310:Acute toxicity,dermal H311:Acute toxicity,dermal H314:Skin corrosion/irritation H318:Serious eye damage/eye irritation H330:Acute toxicity,inhalation H331:Acute toxicity,inhalation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P310:Immediately call a POISON CENTER or doctor/physician. P320:Specific treatment is urgent (see … on this label). P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.