4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-5-ONE

CAS NO.：15646-46-5
Empirical Formula: C12H11NO3
Molecular Weight: 217.22
MDL number: MFCD00003204
EINECS: 239-713-9
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-05 08:26:49

What is 4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-5-ONE?

Chemical properties

white to orange or pink powder

The Uses of 4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-5-ONE

4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one has been used as a haptenizing agent, which can induce an inflammatory reaction in adult zebrafish intestinal tissues and this can be used as a model for gene expression studies of the two forms of inflammatory bowel disease like Crohn′s disease and ulcerative colitis.

The Uses of 4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-5-ONE

4-Ethoxymethylene-2-phenyloxazolin-5-one acts as sensitizing agent. It is also used as pharmaceutical intermediates.

What are the applications of Application

4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one is a sensitizing agent

Definition

ChEBI: A 1,3-oxazole compound having a phenyl substituent at the 2-position, an ethoxymethylene group at the 4-position, and an oxo group at the 5-position. It is a chemical allergen used for immunological experiments, particularly for experiments on delayed typ hypersensitivity.

Properties of 4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-5-ONE

Melting point:	94-96 °C (dec.)(lit.)
Boiling point:	357.77°C (rough estimate)
Density	1.2160 (rough estimate)
refractive index	1.5560 (estimate)
storage temp.	2-8°C
form	Solid
pka	-2.59±0.20(Predicted)
form	neat
color	Gray to brown
Water Solubility	Soluble in methanol (50 mg/ml), and water (partly).
BRN	163055
CAS DataBase Reference	15646-46-5(CAS DataBase Reference)

Safety information for 4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-5-ONE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H317:Sensitisation, Skin
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection.