4-Ethoxybenzaldehyde
- CAS NO.:10031-82-0
- Empirical Formula: C9H10O2
- Molecular Weight: 150.17
- MDL number: MFCD00003388
- EINECS: 233-093-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-04-09 22:15:29
What is 4-Ethoxybenzaldehyde?
Description
4-Ethoxybenzaldehyde is a flavoring ingredient. 4-Ethoxybenzaldehyde can be used as an anti-inflammatory and prostaglandin E2 suppressor. It has also been indicated that it is useful in reducing facial erythema.
Chemical properties
clear yellow to light brown liquid
Chemical properties
p-Ethoxybenzaldehyde has a sweet, floral, and anise odor and a similar taste
Occurrence
Reported found in black tea
The Uses of 4-Ethoxybenzaldehyde
4-Ethoxybenzaldehyde was used as an anti-inflammatory and prostaglandin E2 suppressor in skin lightening agents.
What are the applications of Application
4-Ethoxybenzaldehyde is an antiinflammatory compound
Preparation
By ethylation of p-hydroxybenzaldehyde using aluminum chloride catalyst.
Definition
ChEBI: 4-ethoxybenzaldehyde is an aromatic ether.
Synthesis
p-Ethoxybenzaldehyde is synthesized by Ethylation of para-Hydroxybenzaldehyde. This aldehyde, which is very important as an intermediate in the manufacture of many naturally occurring flavor chemicals can be prepared from Phenol plus Hydrocyanic acid plus Hydrochloric acid.
References
Makino, Elizabeth T., et al. "Evaluation of a hydroquinone-free skin brightening product using in vitro inhibition of melanogenesis and clinical reduction of ultraviolet-induced hyperpigmentation." Journal of drugs in dermatology: JDD 12.3 (2013): s16-20.
Draelos, Zoe Diana, and Bryan B. Fuller. "Efficacy of 1% 4‐Ethoxybenzaldehyde in Reducing Facial Erythema." Dermatologic surgery31.s1 (2005): 881-886.
Cadby, P. "Estimating intakes of flavouring substances." (1996): 453-460.
Properties of 4-Ethoxybenzaldehyde
Melting point: | 13-14 °C(lit.) |
Boiling point: | 255 °C(lit.) |
Density | 1.08 g/mL at 25 °C(lit.) |
refractive index | n |
FEMA | 2413 | P-ETHOXYBENZALDEHYDE |
Flash point: | >230 °F |
storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
form | Liquid |
color | Clear yellow to light brown |
Specific Gravity | 1.08 |
Odor | at 100.00 %. sweet spicy floral anisic |
Water Solubility | Insoluble in water. |
Sensitive | Air Sensitive |
JECFA Number | 879 |
BRN | 386863 |
CAS DataBase Reference | 10031-82-0(CAS DataBase Reference) |
NIST Chemistry Reference | Benzaldehyde, 4-ethoxy-(10031-82-0) |
EPA Substance Registry System | Benzaldehyde, 4-ethoxy- (10031-82-0) |
Safety information for 4-Ethoxybenzaldehyde
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4-Ethoxybenzaldehyde
Abamectin manufacturer
Syn Finechem Laboratories Pvt Ltd.
Saasta Life Sciences
Dr R R Organics
BASR Fine Chemicals Pvt. Ltd.
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