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HomeProduct name list4-Ethoxybenzaldehyde

4-Ethoxybenzaldehyde

  • CAS NO.:10031-82-0
  • Empirical Formula: C9H10O2
  • Molecular Weight: 150.17
  • MDL number: MFCD00003388
  • EINECS: 233-093-3
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-04-09 22:15:29
4-Ethoxybenzaldehyde Structural

What is 4-Ethoxybenzaldehyde?

Description

4-Ethoxybenzaldehyde is a flavoring ingredient. 4-Ethoxybenzaldehyde can be used as an anti-inflammatory and prostaglandin E2 suppressor. It has also been indicated that it is useful in reducing facial erythema.

Chemical properties

clear yellow to light brown liquid

Chemical properties

p-Ethoxybenzaldehyde has a sweet, floral, and anise odor and a similar taste

Occurrence

Reported found in black tea

The Uses of 4-Ethoxybenzaldehyde

4-Ethoxybenzaldehyde was used as an anti-inflammatory and prostaglandin E2 suppressor in skin lightening agents.

What are the applications of Application

4-Ethoxybenzaldehyde is an antiinflammatory compound

Preparation

By ethylation of p-hydroxybenzaldehyde using aluminum chloride catalyst.

Definition

ChEBI: 4-ethoxybenzaldehyde is an aromatic ether.

Synthesis

p-Ethoxybenzaldehyde is synthesized by Ethylation of para-Hydroxybenzaldehyde. This aldehyde, which is very important as an intermediate in the manufacture of many naturally occurring flavor chemicals can be prepared from Phenol plus Hydrocyanic acid plus Hydrochloric acid.

References

Makino, Elizabeth T., et al. "Evaluation of a hydroquinone-free skin brightening product using in vitro inhibition of melanogenesis and clinical reduction of ultraviolet-induced hyperpigmentation." Journal of drugs in dermatology: JDD 12.3 (2013): s16-20.
Draelos, Zoe Diana, and Bryan B. Fuller. "Efficacy of 1% 4‐Ethoxybenzaldehyde in Reducing Facial Erythema." Dermatologic surgery31.s1 (2005): 881-886.
Cadby, P. "Estimating intakes of flavouring substances." (1996): 453-460.

Properties of 4-Ethoxybenzaldehyde

Melting point: 13-14 °C(lit.)
Boiling point: 255 °C(lit.)
Density  1.08 g/mL at 25 °C(lit.)
refractive index  n20/D 1.559(lit.)
FEMA  2413 | P-ETHOXYBENZALDEHYDE
Flash point: >230 °F
storage temp.  under inert gas (nitrogen or Argon) at 2-8°C
form  Liquid
color  Clear yellow to light brown
Specific Gravity 1.08
Odor at 100.00 %. sweet spicy floral anisic
Water Solubility  Insoluble in water.
Sensitive  Air Sensitive
JECFA Number 879
BRN  386863
CAS DataBase Reference 10031-82-0(CAS DataBase Reference)
NIST Chemistry Reference Benzaldehyde, 4-ethoxy-(10031-82-0)
EPA Substance Registry System Benzaldehyde, 4-ethoxy- (10031-82-0)

Safety information for 4-Ethoxybenzaldehyde

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 4-Ethoxybenzaldehyde

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