4-(Chloromethyl)benzoyl chloride
- CAS NO.：876-08-4
- Empirical Formula: C8H6Cl2O
- Molecular Weight: 189.04
- MDL number: MFCD00053224
- EINECS: 212-881-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-14 18:30:21
What is 4-(Chloromethyl)benzoyl chloride?
Chemical properties
white to light beige low melting crystalline mass
The Uses of 4-(Chloromethyl)benzoyl chloride
4-(Chloromethyl)benzoyl Chloride is used in the synthetic preparation of various compounds and pharmaceuticals. 4-(Chloromethyl)benzoyl Chloride was used in the synthesis of several imidazo[2,1-b]thia zoles.
The Uses of 4-(Chloromethyl)benzoyl chloride
4-(Chloromethyl)benzoyl chloride was used as an atom transfer radical polymerization (ATRP) initiator in the growth of polyacrylamide (PAAm) brushes from silicon wafers. It was also used as a building block in a microwave-assisted, solid-phase synthesis of imatinib, an anticancer agent.
What are the applications of Application
4-(Chloromethyl)benzoyl chloride is An atom transfer radical polymerization (ATRP) initiator.
Properties of 4-(Chloromethyl)benzoyl chloride
| Melting point: | 30-32 °C(lit.) |
| Boiling point: | 126-128 °C6 mm Hg(lit.) |
| Density | 1.2979 (rough estimate) |
| refractive index | 1.5605 (estimate) |
| Flash point: | 199 °F |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | soluble in Toluene |
| form | Low Melting Crystalline Mass |
| color | White to light beige |
| CAS DataBase Reference | 876-08-4(CAS DataBase Reference) |
Safety information for 4-(Chloromethyl)benzoyl chloride
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H314:Skin corrosion/irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4-(Chloromethyl)benzoyl chloride
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