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HomeProduct name list4-Chloro-N-methylpiperidine

4-Chloro-N-methylpiperidine

  • CAS NO.:5570-77-4
  • Empirical Formula: C6H12ClN
  • Molecular Weight: 133.62
  • MDL number: MFCD00044489
  • EINECS: 226-942-4
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-06-12 11:13:47
4-Chloro-N-methylpiperidine Structural

What is 4-Chloro-N-methylpiperidine?

Chemical properties

Clear colorless liquid

The Uses of 4-Chloro-N-methylpiperidine

4-Chloro-1-methylpiperidine is a reactant in the synthesis of indole and benzimidazole piperazines as histamine H4 receptor antagonist.

Flammability and Explosibility

Not classified

Physiological effects

4-Chloro-N-methylpiperidine can be used to treat bronchial asthma, chronic obstructive pulmonary disease, and other respiratory disorders by inhibiting the production of histamine in the body. It also has antihistaminic effects that may be due to its ability to inhibit histamine release from mast cells or block H1 receptors.

Properties of 4-Chloro-N-methylpiperidine

Melting point: 160-165°C
Boiling point: 162°C(lit.)
Density  1.02
vapor pressure  3.493hPa at 25℃
refractive index  1.4670-1.4710
Flash point: 48 °C
storage temp.  Inert atmosphere,Room Temperature
solubility  Chloroform (Slightly), Ethanol (Slightly) , Methanol (Slightly)
pka 7.88±0.10(Predicted)
form  clear liquid to slightly cloudy liquid
color  Colorless to Light yellow to Light orange
Water Solubility  1.533g/L at 29℃
CAS DataBase Reference 5570-77-4(CAS DataBase Reference)
EPA Substance Registry System Piperidine, 4-chloro-1-methyl- (5570-77-4)

Safety information for 4-Chloro-N-methylpiperidine

Signal word Warning
Pictogram(s)
ghs
Flame
Flammables
GHS02
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H226:Flammable liquids
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
Precautionary Statement Codes P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233:Keep container tightly closed.
P240:Ground/bond container and receiving equipment.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P370+P378:In case of fire: Use … for extinction.
P403+P235:Store in a well-ventilated place. Keep cool.
P501:Dispose of contents/container to..…

Computed Descriptors for 4-Chloro-N-methylpiperidine

InChIKey MYGXGCCFTPKWIH-UHFFFAOYSA-N

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