4-Chloro-N-methylpiperidine
- CAS NO.：5570-77-4
- Empirical Formula: C6H12ClN
- Molecular Weight: 133.62
- MDL number: MFCD00044489
- EINECS: 226-942-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-09-25 17:15:13
What is 4-Chloro-N-methylpiperidine?
Chemical properties
Clear colorless liquid
The Uses of 4-Chloro-N-methylpiperidine
4-Chloro-1-methylpiperidine is a reactant in the synthesis of indole and benzimidazole piperazines as histamine H4 receptor antagonist.
Flammability and Explosibility
Not classified
Physiological effects
4-Chloro-N-methylpiperidine can be used to treat bronchial asthma, chronic obstructive pulmonary disease, and other respiratory disorders by inhibiting the production of histamine in the body. It also has antihistaminic effects that may be due to its ability to inhibit histamine release from mast cells or block H1 receptors.
Properties of 4-Chloro-N-methylpiperidine
| Melting point: | 160-165°C |
| Boiling point: | 162°C(lit.) |
| Density | 1.02 |
| vapor pressure | 3.493hPa at 25℃ |
| refractive index | 1.4670-1.4710 |
| Flash point: | 48 °C |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Chloroform (Slightly), Ethanol (Slightly) , Methanol (Slightly) |
| pka | 7.88±0.10(Predicted) |
| form | clear liquid to slightly cloudy liquid |
| color | Colorless to Light yellow to Light orange |
| Water Solubility | 1.533g/L at 29℃ |
| CAS DataBase Reference | 5570-77-4(CAS DataBase Reference) |
| EPA Substance Registry System | Piperidine, 4-chloro-1-methyl- (5570-77-4) |
Safety information for 4-Chloro-N-methylpiperidine
| Signal word | Warning |
| Pictogram(s) |
 Flame Flammables GHS02  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H226:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P370+P378:In case of fire: Use … for extinction. P403+P235:Store in a well-ventilated place. Keep cool. P501:Dispose of contents/container to..… |
Computed Descriptors for 4-Chloro-N-methylpiperidine
| InChIKey | MYGXGCCFTPKWIH-UHFFFAOYSA-N |
4-Chloro-N-methylpiperidine manufacturer
Global Chemie
Mumbai
Phone:91-9924260171
Whatsapp: 91-9924260171
product: 1-Methyl-4-chloropiperidine
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