4-Bromobenzyl alcohol

Chemical properties

A light yellow crystalline, it is chemically stable under standard ambient conditions (room temperature) .

The Uses of 4-Bromobenzyl alcohol

4-Bromobenzyl alcohol was used in the synthesis of:

• hydroxyl end functionalized, substituted polyfluorene
• amphiphilic, symmetric rod-coil, triblock copolymer of poly(9,9-didodecylfluorene-2,7-diyl) and poly(hydroxyl ethyl methacrylate)

Synthesis Reference(s)

The Journal of Organic Chemistry, 48, p. 3074, 1983 DOI: 10.1021/jo00166a029
Tetrahedron Letters, 36, p. 3169, 1995 DOI: 10.1016/0040-4039(95)00504-6

General Description

4-Bromobenzyl alcohol undergoes three-component reaction with acetylferrocene and arylboronic acid to give ferrocenyl ketones containing biaryls. It undergoes oxidation reaction in the presence of polyvinylpolypyrrolidone-supported hydrogen peroxide, silica sulfuric acid and ammonium bromide to yield 4-bromobenzaldehyde. It undergoes efficient trimethylsilylation reaction with 1,1,1,3,3,3-hexamethyldisilazane in the presence of catalytic amount of aspartic acid in acetonitrile.

Flammability and Explosibility

Not classified

Reactions

4-Bromobenzyl alcohol is a reactive chemical that reacts with water to form the hydroxyl group and hydrogen bond. It has been shown to inhibit the reaction of ethyl formate with biphenyl by cleaving the molecule and forming a new site specific.