4-AZIDOPHENACYL BROMIDE

Synonym(s):4′-Azido-2-bromoacetophenone;4-Azido-α-bromoacetophenone

CAS NO.：57018-46-9
Empirical Formula: C8H6BrN3O
Molecular Weight: 240.06
MDL number: MFCD00042637
EINECS: 260-519-5
SAFETY DATA SHEET (SDS)
Update Date: 2023-05-15 10:43:34

What is 4-AZIDOPHENACYL BROMIDE?

Chemical properties

4-AZIDOPHENACYL BROMIDE is off-White Crystalline Solid

The Uses of 4-AZIDOPHENACYL BROMIDE

4-AZIDOPHENACYL BROMIDE is a versatile photolabile bifunctional reagent. Useful for investigating the active sites of sulfhydryl enzymes-particularly those which posess a particularly reactive cysteine residue at the active site. Used to study the nature of the ribosomal binding site of E. coli tRNAVal.

The Uses of 4-AZIDOPHENACYL BROMIDE

Photoactive, heterobifunctional cross-linking reagent. Typically, the initial reaction couples to sulfhydryl in the pH range 7.0-8.0. Second bonding occurs during UV irradiation (250 nm) via reactive nitrene. The latter bonding is rapid and non-specific.

What are the applications of Application

p-Azidophenacyl Bromide is an aryl azide-based, sulfhydryl- and photoreactive crosslinker

Properties of 4-AZIDOPHENACYL BROMIDE

Melting point:	64-65 °C
storage temp.	2-8°C
solubility	methanol: 50 mg/mL
form	powder
color	yellow
BRN	1961705
Stability:	Light, Temperature And Moisture Sensitive, Temperature and Moisture sensitive

Safety information for 4-AZIDOPHENACYL BROMIDE

Signal word	Danger
Pictogram(s)	Flame Flammables GHS02 Corrosion Corrosives GHS05 Health Hazard GHS08
GHS Hazard Statements	H228:Flammable solids H314:Skin corrosion/irritation H317:Sensitisation, Skin H334:Sensitisation, respiratory
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P310:Immediately call a POISON CENTER or doctor/physician. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.