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HomeProduct name list4-Aminoguinoline

4-Aminoguinoline

  • CAS NO.:578-68-7
  • Empirical Formula: C9H8N2
  • Molecular Weight: 144.17
  • MDL number: MFCD00463448
  • EINECS: 640-116-4
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-06-08 17:06:38
4-Aminoguinoline Structural

What is 4-Aminoguinoline?

Chemical properties

Light brown to grey solid

The Uses of 4-Aminoguinoline

4-Quinolinamine and its derivatives are commonly used as anti-malarial drugs and also have potential therapeutic effects on patients afflicted with arthritis (and/or related diseases).

What are the applications of Application

4-Aminoquinoline is a variety of derivatives of 4-aminoquinoline are antimalarial agents

Synthesis Reference(s)

Journal of Medicinal Chemistry, 43, p. 4667, 2000 DOI: 10.1021/jm0002073
Tetrahedron Letters, 39, p. 1313, 1998 DOI: 10.1016/S0040-4039(97)10877-2

Purification Methods

It has been purified by zone refining and recrystallisation from *C6H6, EtOH or H2O. The hydrochloride has m 308o (from MeOH), and the picrate has m 277o (from EtOH). [Albert et al. J Chem Soc 2240 1948, Beilstein 22 III/IV 4611, 22/10 V 341.]

Properties of 4-Aminoguinoline

Melting point: 151.0 and le 155.0 °C
Boiling point: 312.78°C (estimate)
Density  1.1148 (estimate)
refractive index  1.7080 (estimate)
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
pka 9.17(at 20℃)
form  powder to crystalline
color  White to Yellow to Orange
CAS DataBase Reference 578-68-7(CAS DataBase Reference)

Safety information for 4-Aminoguinoline

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.

Computed Descriptors for 4-Aminoguinoline

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