5-Aminoquinoline
Synonym(s):5-Quinolinamine
- CAS NO.：611-34-7
- Empirical Formula: C9H8N2
- Molecular Weight: 144.17
- MDL number: MFCD00006797
- EINECS: 210-266-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-27 16:27:43
What is 5-Aminoquinoline?
Chemical properties
Reddish-Brown Solid
The Uses of 5-Aminoquinoline
Intermediate in the preparation of P2X7 antagonists
What are the applications of Application
5-Aminoquinoline is an intermediate in the preparation of P2X7 antagonists
What are the applications of Application
5-Aminoquinoline can be used as organic synthesis and as intermediates of medicine and pesticide.
Preparation
Under the catalysis of Pd/C, 95% ethanol was used as solvent to reduce 5-nitroquinoline with hydrazine hydrate to synthesize 5-aminoquinoline with a yield of 91.11%.
Properties of 5-Aminoquinoline
| Melting point: | 106-109 °C (lit.) |
| Boiling point: | 310 °C (lit.) |
| Density | 1.1148 (estimate) |
| refractive index | 1.7080 (estimate) |
| Flash point: | 310°C |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMSO, Methanol |
| form | Crystalline Powder or Granules |
| pka | pK1: 5.46(+1) (20°C,μ=0.01) |
| color | White to slightly yellow |
| Sensitive | Air Sensitive |
| BRN | 114479 |
| CAS DataBase Reference | 611-34-7(CAS DataBase Reference) |
| NIST Chemistry Reference | 5-Quinolinamine(611-34-7) |
Safety information for 5-Aminoquinoline
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for 5-Aminoquinoline
5-Aminoquinoline manufacturer
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