4'-Aminoacetanilide

Synonym(s):N-(4-Aminophenyl)acetamide;N-Acetyl-p-phenylenediamine

CAS NO.：122-80-5
Empirical Formula: C8H10N2O
Molecular Weight: 150.18
MDL number: MFCD00007853
EINECS: 204-576-6
SAFETY DATA SHEET (SDS)
Update Date: 2023-06-20 22:47:09

What is 4'-Aminoacetanilide?

Chemical properties

PINK TO BROWN FINE CRYSTALLINE POWDER

The Uses of 4'-Aminoacetanilide

Intermediate in the manufacture of azo dyes, pharmaceuticals.

General Description

White or slightly reddish solid.

Air & Water Reactions

Slightly soluble in water.

Reactivity Profile

Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

Hazard

Moderate toxicity by ingestion.

Fire Hazard

Flash point data are not available for 4'-Aminoacetanilide, but 4'-Aminoacetanilide is probably combustible.

Purification Methods

Crystallise the anilide from water. It has an unstable crystalline form with m 141o. It has IR: max (CCl4) 1681cm-1. [Beilstein 13 H 94, 13 I 28, 13 II 50, 13 III 166, 13 IV 137.]

Properties of 4'-Aminoacetanilide

Melting point:	164-167 °C(lit.)
Boiling point:	267 °C
Density	1.1392 (rough estimate)
refractive index	1.6180 (estimate)
Flash point:	195°C
storage temp.	Store below +30°C.
solubility	65g/l slightly soluble
form	Fine Crystalline Powder
pka	14.75±0.70(Predicted)
Colour Index	76005
color	Pink to brown
PH	7.2 (1g/l, H2O, 20℃)
Water Solubility	0.1-1 g/100 mL at 25 ºC
Sensitive	Air Sensitive
Merck	14,411
BRN	742888
CAS DataBase Reference	122-80-5(CAS DataBase Reference)
NIST Chemistry Reference	Acetamide, N-(4-aminophenyl)-(122-80-5)
EPA Substance Registry System	4'-Aminoacetanilide (122-80-5)

Safety information for 4'-Aminoacetanilide

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.