4'-Aminoacetanilide
Synonym(s):N-(4-Aminophenyl)acetamide;N-Acetyl-p-phenylenediamine
- CAS NO.：122-80-5
- Empirical Formula: C8H10N2O
- Molecular Weight: 150.18
- MDL number: MFCD00007853
- EINECS: 204-576-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 14:15:30
What is 4'-Aminoacetanilide?
Chemical properties
PINK TO BROWN FINE CRYSTALLINE POWDER
The Uses of 4'-Aminoacetanilide
Intermediate in the manufacture of azo dyes, pharmaceuticals.
General Description
White or slightly reddish solid.
Air & Water Reactions
Slightly soluble in water.
Reactivity Profile
Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
Hazard
Moderate toxicity by ingestion.
Fire Hazard
Flash point data are not available for 4'-Aminoacetanilide, but 4'-Aminoacetanilide is probably combustible.
Purification Methods
Crystallise the anilide from water. It has an unstable crystalline form with m 141o. It has IR: max (CCl4) 1681cm-1. [Beilstein 13 H 94, 13 I 28, 13 II 50, 13 III 166, 13 IV 137.]
Properties of 4'-Aminoacetanilide
| Melting point: | 164-167 °C(lit.) |
| Boiling point: | 267 °C |
| Density | 1.1392 (rough estimate) |
| refractive index | 1.6180 (estimate) |
| Flash point: | 195°C |
| storage temp. | Store below +30°C. |
| solubility | 65g/l slightly soluble |
| form | Fine Crystalline Powder |
| pka | 14.75±0.70(Predicted) |
| Colour Index | 76005 |
| color | Pink to brown |
| PH | 7.2 (1g/l, H2O, 20℃) |
| Water Solubility | 0.1-1 g/100 mL at 25 ºC |
| Sensitive | Air Sensitive |
| Merck | 14,411 |
| BRN | 742888 |
| CAS DataBase Reference | 122-80-5(CAS DataBase Reference) |
| NIST Chemistry Reference | Acetamide, N-(4-aminophenyl)-(122-80-5) |
| EPA Substance Registry System | 4'-Aminoacetanilide (122-80-5) |
Safety information for 4'-Aminoacetanilide
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4'-Aminoacetanilide
4'-Aminoacetanilide manufacturer
Jackson Chemical Industries
Intersperse Industries
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