4-Amino-3,5-dichlorophenacylbromide
- CAS NO.：37148-47-3
- Empirical Formula: C8H6BrCl2NO
- Molecular Weight: 282.95
- MDL number: MFCD09743795
- EINECS: 253-367-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-09-23 15:54:53
What is 4-Amino-3,5-dichlorophenacylbromide?
Chemical properties
Yellow Solid
The Uses of 4-Amino-3,5-dichlorophenacylbromide
1-(4-Amino-3,5-dichlorophenyl)-2-bromoethanone Hydrobromide is an intermediate in synthesizing Clenproperol-d7 (C573002). A labelled related drug of Clenbuterol (C569998), a β-agonist which can be used as a growth promoter in farm animals.
The Uses of 4-Amino-3,5-dichlorophenacylbromide
4-Amino-3,5-dichloro-alpha-bromoacetophenone is an impurity reference for Clenbuterol and can be used as a reference substance to analyze drug quality. It is widely used in organic synthesis and drug production.
Preparation
Dissolve 4-amino-3, 5-dichloroacetophenone in chloroform and heat to 65°C. Add bromine dropwise with stirring, stir for a few minutes after adding, then add ethanol and stir. Freeze, filter out the crystals, wash with chloroform, and dry at low temperature to obtain finished products.
Properties of 4-Amino-3,5-dichlorophenacylbromide
| Melting point: | 142-1450C |
| Boiling point: | 396.4±42.0 °C(Predicted) |
| Density | 1.764±0.06 g/cm3(Predicted) |
| storage temp. | -20°C Freezer, Under Inert Atmosphere |
| solubility | DMSO (Slightly), Ethyl Acetate (Slightly) |
| form | Solid |
| pka | -2.21±0.10(Predicted) |
| color | Off-White to Yellow |
| Stability: | Moisture Sensitive |
| InChI | InChI=1S/C8H6BrCl2NO/c9-3-7(13)4-1-5(10)8(12)6(11)2-4/h1-2H,3,12H2 |
| CAS DataBase Reference | 37148-47-3 |
Safety information for 4-Amino-3,5-dichlorophenacylbromide
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4-Amino-3,5-dichlorophenacylbromide
| InChIKey | ATKJJUFAWYSFID-UHFFFAOYSA-N |
| SMILES | C(=O)(C1=CC(Cl)=C(N)C(Cl)=C1)CBr |
New Products
4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Mefenamic Acid IP/BP/EP/USP Diclofenac Sodium IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
![1-(4-amino-3,5-dichlorophenyl)-2-[(1,1-dimethylethyl)amino]ethan-1-one hydrochloride](https://img.chemicalbook.in/CAS/GIF/37148-49-5.gif)
You may like
-
1-Methyl-6-oxo-1,6-dihydropyridazine-3-carbonitrile 98%View Details
99903-60-3 -
88491-46-7 98%View Details
88491-46-7 -
1823368-42-8 98%View Details
1823368-42-8 -
2-(3-(tert-butyl)phenoxy)-2-methylpropanoic acid 1307449-08-6 98%View Details
1307449-08-6 -
Ethyl 3-(furan-2-yl)-3-hydroxypropanoate 25408-95-1 98%View Details
25408-95-1 -
2-Chloro-5-fluoro-1-methoxy-3-methylbenzene 98%View Details
1805639-70-6 -
1784294-80-9 98%View Details
1784294-80-9 -
Lithium ClavulanateView Details
61177-44-4
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.