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HomeProduct name list4-Amino-1-Boc-piperidine

4-Amino-1-Boc-piperidine

Synonym(s):tert-Butyl 4-amino-1-piperidinecarboxylate;1-Boc-4-piperidinamine

  • CAS NO.:87120-72-7
  • Empirical Formula: C10H20N2O2
  • Molecular Weight: 200.28
  • MDL number: MFCD01076201
  • EINECS: 1312995-182-4
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-05-30 19:23:35
4-Amino-1-Boc-piperidine Structural

What is 4-Amino-1-Boc-piperidine?

Chemical properties

white to light yellow crystal powder

The Uses of 4-Amino-1-Boc-piperidine

4-Amino-1-Boc-piperidine is a chemical reagent used in the preparation of pharmaceutical compounds. Used in the synthesis of bromodomain inhibitors as well as HepG2 cell cycle inhibitors used in anti-tumor therapy. Also employed in a microwave-assisted solid-phase synthesis of N-substituted piperidines via direct annulation of primary amines with resin-bound dimesylates.

The Uses of 4-Amino-1-Boc-piperidine

4-Amino-1-Boc-piperidine is a potent inhibitor of the CCR5 receptor. It is an x-ray crystal structure with a hydroxide solution that inhibits the growth of cancer cells. The inhibitor binding site for 4-Amino-1-Boc-piperidine was determined to be the CCR5 receptor, which is located on the surface of hematopoietic cells. The compound has been shown to inhibit human T lymphocyte proliferation in vitro and inhibit HIV replication in infected patients. 4-Amino-1-Boc-piperidine is able to inhibit the growth of cancer cells by blocking the production of cytokines, such as interleukin 2, that are needed for cell division and growth.

What are the applications of Application

4-Amino-1-Boc-piperidine is a pharmaceutical intermediate is applied in the treatment of anti-tumor and other drugs. It is an important fine chemical intermediate and has a wide range of uses in the pharmaceutical industry.

Properties of 4-Amino-1-Boc-piperidine

Melting point: 50°C
Boiling point: 80/0.037mm
Density  1.041±0.06 g/cm3(Predicted)
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
form  Crystalline Powder, Crystals and/or Chunks
pka 10.10±0.20(Predicted)
color  White to pale yellow to beige
Water Solubility  Insoluble in water.
Sensitive  Air Sensitive
InChI InChI=1S/C10H20N2O2/c1-10(2,3)14-9(13)12-6-4-8(11)5-7-12/h8H,4-7,11H2,1-3H3
CAS DataBase Reference 87120-72-7(CAS DataBase Reference)

Safety information for 4-Amino-1-Boc-piperidine

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H318:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.

Computed Descriptors for 4-Amino-1-Boc-piperidine

InChIKey LZRDHSFPLUWYAX-UHFFFAOYSA-N
SMILES N1(C(OC(C)(C)C)=O)CCC(N)CC1

4-Amino-1-Boc-piperidine manufacturer

TAGOOR LABORATORIES PVT LTD

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Phone:+91-9505502670
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JSK Chemicals

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Sam Fine O Chem Limited

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Stereokem Pvt Ltd

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Chemtrak Life Sciences Private Limited

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Anand Agencies

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