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HomeProduct name list1-tert-Butoxycarbonyl-4-piperidinecarboxaldehyde

1-tert-Butoxycarbonyl-4-piperidinecarboxaldehyde

  • CAS NO.:137076-22-3
  • Empirical Formula: C11H19NO3
  • Molecular Weight: 213.27
  • MDL number: MFCD02179019
  • EINECS: 203-107-6
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-03-11 17:00:25
1-tert-Butoxycarbonyl-4-piperidinecarboxaldehyde Structural

What is 1-tert-Butoxycarbonyl-4-piperidinecarboxaldehyde?

Chemical properties

Clear Yellow Oil

The Uses of 1-tert-Butoxycarbonyl-4-piperidinecarboxaldehyde

Reactant for synthesis of:• ;Pim-1 inhibitors1• ;Selective GPR119 agonists for type II diabetes2• ;M-tropic (R5) HIV-1 replication inhibitors3• ;HDAC inhibitors4• ;Selective 5-HT6 antagonists5Reactant for three-component vinylogous Mannich reactions6

The Uses of 1-tert-Butoxycarbonyl-4-piperidinecarboxaldehyde

1-Boc-piperidine-4-carboxaldehyde is used as reactant for synthesis of Pim-1 inhibitors, selective GPR119 agonists for type II diabetes, M-tropic (R5) HIV-1 replication inhibitors, HDAC inhibitors and selective 5-HT6 antagonists. It is also used as reactant for three-component vinylogous Mannich reactions

The Uses of 1-tert-Butoxycarbonyl-4-piperidinecarboxaldehyde

An intermediate for polycyclic indazole derivatives that are ERK inhibitors.

Properties of 1-tert-Butoxycarbonyl-4-piperidinecarboxaldehyde

Melting point: 34-40℃
Boiling point: 295.4±33.0 °C(Predicted)
Density  1.114±0.06 g/cm3(Predicted)
Flash point: >110℃
storage temp.  2-8°C
solubility  Soluble in methanol.
form  Oil
pka -2.13±0.40(Predicted)
color  Clear Yellow
Sensitive  Air Sensitive
CAS DataBase Reference 137076-22-3(CAS DataBase Reference)

Safety information for 1-tert-Butoxycarbonyl-4-piperidinecarboxaldehyde

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
ghs
Environment
GHS09
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
H410:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes P273:Avoid release to the environment.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 1-tert-Butoxycarbonyl-4-piperidinecarboxaldehyde

InChIKey JYUQEWCJWDGCRX-UHFFFAOYSA-N

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