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HomeProduct name list4-Acetamidophenylboronic acid

4-Acetamidophenylboronic acid

Synonym(s):4-Acetamidobenzeneboronic acid

4-Acetamidophenylboronic acid Structural

What is 4-Acetamidophenylboronic acid?

Chemical properties

White to light yellow crystal powde

The Uses of 4-Acetamidophenylboronic acid

Reactant involved in:

  • Synthesis of TpI2 kinase inhibitors
  • Biological evaluation of modulators of survival motor neuron protein
  • Cross-coupling with conjugated dienes or terminal alkenes or diazoesters
  • Synthesis of tetrabutylammonium trifluoroborates
  • Rhosium-catalyzed cyanation

The Uses of 4-Acetamidophenylboronic acid

4-Acetamidophenylboronic Acid is used in the synthesis of potent chrom-4-one inhibitors of the DNA-Dependant protein kinase for use in radiotherapy and chemotherapy in cancer treatment.

Properties of 4-Acetamidophenylboronic acid

Melting point: 215-220 °C (lit.)
Density  1.23±0.1 g/cm3(Predicted)
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
pka 8.63±0.10(Predicted)
form  Powder
color  Gray-tan
Water Solubility  85 g/L (70 ºC)
CAS DataBase Reference 101251-09-6(CAS DataBase Reference)

Safety information for 4-Acetamidophenylboronic acid

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405:Store locked up.

Computed Descriptors for 4-Acetamidophenylboronic acid

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