4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride
- CAS NO.：106261-64-7
- Empirical Formula: C13H18Cl2N2O
- Molecular Weight: 289.2
- MDL number: MFCD11519983
- EINECS: 680-808-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-13 21:11:14
What is 4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride?
The Uses of 4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride
4-((4-Methylpiperazin-1-yl)methyl)benzoyl Chloride Dihydrochloride is an intermediate in the synthesis of Gleevec N-4-((4-Methylpiperazin-1-yl)methyl)benzaldehyde (G407010), an impurity of Gleevec (G407000), a tyrosine kinase inhibitor which is highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL).
Properties of 4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride
| Melting point: | >240°C (dec.) |
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | DMSO (Slightly) |
| form | Solid |
| color | White to Off-White |
| Water Solubility | 100vol% at 20℃[vol%] |
| Stability: | Hygroscopic, Moisture Sensitive |
Safety information for 4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P310:Immediately call a POISON CENTER or doctor/physician. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride
4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride manufacturer
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