(3alpha,4beta)-3-(Acetyloxy)olean-12-en-23-oic acid
Synonym(s):α-Boswellic acid acetate;(3α,4β)-3-(Acetyloxy)olean-12-en-23-oic acid;3α-(Acetyloxy)olean-12-en-24-oic acid
- CAS NO.：89913-60-0
- Empirical Formula: C32H50O4
- Molecular Weight: 498.74
- MDL number: MFCD03788772
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:55:03
What is (3alpha,4beta)-3-(Acetyloxy)olean-12-en-23-oic acid?
Description
α-acetyl Boswellic acid is a pentacyclic triterpene and isomer of β-acetyl-boswellic acid originally isolated from B. serrata. It inhibits LPS-induced TNF-α mRNA expression in monocytes as well as NF-κB activity in HEK293 cells when used at a concentration of 10 μM. α-acetyl Boswellic acid also inhibits phosphorylation of IκBα mediated by IκB kinases (IKKs) in monocytes.
The Uses of (3alpha,4beta)-3-(Acetyloxy)olean-12-en-23-oic acid
Acetyl-α-boswellic Acid is a selective inhibitor of COX-1. It also inhibits NF-KB signaling in LPS-stimulated monocytes.
Definition
ChEBI: 3-alpha-O-acetyl-alpha-boswellic acid is a triterpenoid. It has a role as a metabolite.
Properties of (3alpha,4beta)-3-(Acetyloxy)olean-12-en-23-oic acid
| Melting point: | 230-232℃ |
| Boiling point: | 563.6±50.0 °C(Predicted) |
| Density | 1.10 |
| storage temp. | Refrigerator |
| solubility | Chloroform (Slightly) |
| form | neat |
| pka | 4.32±0.70(Predicted) |
| form | Solid |
| color | White to Off-White |
Safety information for (3alpha,4beta)-3-(Acetyloxy)olean-12-en-23-oic acid
Computed Descriptors for (3alpha,4beta)-3-(Acetyloxy)olean-12-en-23-oic acid
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