3,6,9,12,15,18,21,24,27,30,33-Undecaoxatetratriacontan-1-amine
- CAS NO.：854601-60-8
- Empirical Formula: C23H49NO11
- Molecular Weight: 515.64
- MDL number: MFCD27977521
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 23:16:16
What is 3,6,9,12,15,18,21,24,27,30,33-Undecaoxatetratriacontan-1-amine?
Description
m-PEG11-amine is a water soluble PEG linker containing an amino group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The hydrophilic PEG spacer increases solubility in aqueous media.
Biological Activity
M-PEG11-Amino is a cleavable ADC linker for the synthesis of antibody-drug conjugates (ADCs). It is also a PEG-based PROTAC linker that can be used for PROTAC synthesis.
in vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins
Properties of 3,6,9,12,15,18,21,24,27,30,33-Undecaoxatetratriacontan-1-amine
| Boiling point: | 551.9±45.0 °C(Predicted) |
| Density | 1.070±0.06 g/cm3(Predicted) |
| form | Solid-Liquid Mixture |
| pka | 8.74±0.10(Predicted) |
| color | Colorless to off-white |
Safety information for 3,6,9,12,15,18,21,24,27,30,33-Undecaoxatetratriacontan-1-amine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 3,6,9,12,15,18,21,24,27,30,33-Undecaoxatetratriacontan-1-amine
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