Decaethylene glycol
- CAS NO.：5579-66-8
- Empirical Formula: C20H42O11
- Molecular Weight: 458.54
- MDL number: MFCD00698693
- EINECS: 226-962-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 14:07:02
What is Decaethylene glycol?
Description
PEG11 is a polymer consisting of 11 ethylene glycol subunits and two terminal hydroxyl groups. The hydroxyl groups can react to further derivatize the compound. The hydrophilic PEG linkers increase the water solubility of the compound under aqueous environments. The water solubility properties of the PEG chain are enhanced with longer chains.
The Uses of Decaethylene glycol
Decaethylene Glycol can be used as a corrosion inhibitor of aluminum surfaces.
Definition
ChEBI: Decaethylene glycol is a poly(ethylene glycol).
What are the applications of Application
Decaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs, which contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase, and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Properties of Decaethylene glycol
| Melting point: | 28 °C |
| Boiling point: | 280 °C / 7mmHg |
| Density | 1.115±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| form | powder to lump to clear liquid |
| pka | 14.06±0.10(Predicted) |
| color | White or Colorless to Almost white or Almost colorless |
| InChI | InChI=1S/C20H42O11/c21-1-3-23-5-7-25-9-11-27-13-15-29-17-19-31-20-18-30-16-14-28-12-10-26-8-6-24-4-2-22/h21-22H,1-20H2 |
| EPA Substance Registry System | Decaethylene glycol (5579-66-8) |
Safety information for Decaethylene glycol
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for Decaethylene glycol
| InChIKey | DTPCFIHYWYONMD-UHFFFAOYSA-N |
| SMILES | C(O)COCCOCCOCCOCCOCCOCCOCCOCCOCCO |
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