3-METHYL-L-HISTIDINE
Synonym(s):π-Methyl-L -histidine;1-Methyl-L -histidine (archaic);3-(1-Methylimidazol-5-yl)-L -alanine
- CAS NO.:368-16-1
- Empirical Formula: C7H11N3O2
- Molecular Weight: 169.18
- MDL number: MFCD08273564
- EINECS: 206-704-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-28 13:53:27
What is 3-METHYL-L-HISTIDINE?
Chemical properties
White to off-white powder
The Uses of 3-METHYL-L-HISTIDINE
3-Methyl-L-histidine is a potential compound to be used as a treatment with pharmacological PPARα agonists to stimulate the ubiquitin proteasome pathway and myofibrillar protein breakdown in skeleta l muscle of rodents.
Definition
ChEBI: A L-histidine derivative that is L-histidine substituted by a methyl group at position 3 on the imidazole ring.
Biochem/physiol Actions
3-Methyl-L-histidine is a non-proteinogenic amino acid and an index of muscle breakdown.
Properties of 3-METHYL-L-HISTIDINE
Melting point: | 248~252℃ |
Boiling point: | 298.47°C (rough estimate) |
alpha | +12.0~+18.0°(20℃/D)(c=2,dil.HCl) |
Density | 1.37 |
refractive index | 1.5950 (estimate) |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
solubility | PBS (pH 7.2): 10 mg/ml |
form | A crystalline solid |
pka | 2.04±0.10(Predicted) |
color | White to off-white |
Stability: | Hygroscopic |
CAS DataBase Reference | 368-16-1(CAS DataBase Reference) |
Safety information for 3-METHYL-L-HISTIDINE
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 3-METHYL-L-HISTIDINE
New Products
Tubulysin H Tubulysin I Tubulysin C 2,2-diethoxyethanethioamide Tubulysin D (S)-(+)-3-HYDROXYTETRAHYDROFURAN 3-METHYLAZETIDIN-3-OL HYDROCHLORIDE 4-Methylenepiperidine HCl tert-Butyl (azetidin-3-yl)carbamate hydrochloride Methyl (R)-1-Boc-4,4-difluoropyrrolidine-2-carboxylate 4-FLUOROPIPERIDINE HYDROCHLORIDE 5-Nitrobarbituric acid 2-Amino-3-bromo-5-nitropyridine N-[2-(Acetylthio)-1-oxobutyl]glycine ethyl ester methyl 2-bromobenzoate 4-chloro-2-hydroxy-5-nitropyridine 5-Bromo-2-chloroisonicotinic acid 7-Methoxyquinoline-4-carbonitrile 7-Methoxyquinoline-4-carboxylic acid 1H-Imidazole-4-carbonitrile (2S)-3-Methyl-2-(methylamino)-1-butanol Solifenacin Ethyl Ester Impurity / Solifenacin Acid Ethyl Ester Quetiapine S-Oxide 7-Hydroxy Metabolite Methylprednisolone Acetate EP Impurity IRelated products of tetrahydrofuran
1-Methyl-L-histidine
Methyl L-histidinate dihydrochloride
H-HIS(BZL)-OH
H-His(Trt)-OMe · HCl
H-HIS(TRT)-OH
1-METHYL-L-HISTIDINE N-HYDRATE
FMOC-D-HIS(MTT)-OH
L-Histidine
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