3-FLUOROPHENYLMAGNESIUM BROMIDE
- CAS NO.：17318-03-5
- Empirical Formula: C6H4BrFMg
- Molecular Weight: 199.3
- MDL number: MFCD00672007
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is 3-FLUOROPHENYLMAGNESIUM BROMIDE?
Chemical properties
Colorless to yellow to orange to brown liquid
The Uses of 3-FLUOROPHENYLMAGNESIUM BROMIDE
3-Fluorophenylmagnesium bromide is used as a Grignard reagent in greener solvent, 2-methyltetrahydrofuran (2-MeTHF).
The Uses of 3-FLUOROPHENYLMAGNESIUM BROMIDE
3-Fluorophenylmagnesium bromide is a Grignard reagent that can be used in:
- The preparation of 4-substituted quinazolines by reacting with 2-methylaminobenzonitriles.
- The synthesis of radiolabeled TrkB/C-targeting kinase inhibitor for positron emission tomography (PET) imaging applications.
- Cu-catalyzed carbometalation of substituted cyclopropenes.
Properties of 3-FLUOROPHENYLMAGNESIUM BROMIDE
| Boiling point: | 65 °C |
| Density | 1.024 g/mL at 25 °C |
| Flash point: | <1 °F |
| storage temp. | 2-8°C |
| Water Solubility | It reacts violently with water. |
| Sensitive | Air & Moisture Sensitive |
| CAS DataBase Reference | 17318-03-5 |
Safety information for 3-FLUOROPHENYLMAGNESIUM BROMIDE
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07  Health Hazard GHS08 |
| GHS Hazard Statements |
H225:Flammable liquids H302:Acute toxicity,oral H314:Skin corrosion/irritation H318:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H351:Carcinogenicity |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P370+P378:In case of fire: Use … for extinction. P405:Store locked up. P403+P235:Store in a well-ventilated place. Keep cool. |
Computed Descriptors for 3-FLUOROPHENYLMAGNESIUM BROMIDE
3-FLUOROPHENYLMAGNESIUM BROMIDE manufacturer
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product: 17318-03-5 3-Fluorophenyl Magnesium Bromide (1.0 M in THF)
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