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HomeProduct name list3-Ethyl-4-methyl-3-pyrrolin-2-one

3-Ethyl-4-methyl-3-pyrrolin-2-one

  • CAS NO.:766-36-9
  • Empirical Formula: C7H11NO
  • Molecular Weight: 125.17
  • MDL number: MFCD00173861
  • EINECS: 616-364-4
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-04-09 22:15:29
3-Ethyl-4-methyl-3-pyrrolin-2-one Structural

What is 3-Ethyl-4-methyl-3-pyrrolin-2-one?

The Uses of 3-Ethyl-4-methyl-3-pyrrolin-2-one

3-Ethyl-4-methyl-3-pyrrolin-2-one is used as an intermediate for the manufacture of medicines. It is used for the preparation of Glimepiride (G410150), and its intermediates and as antidiabetic agents.

What are the applications of Application

3-Ethyl-4-methyl-3-pyrrolin-2-one is a heterocyclic building block

General Description

3-Ethyl-4-methyl-3-pyrrolin-2-one, a five-membered α,β-unsaturated lactam derivative, has various applications in medicinal chemistry. It can be synthesized by employing following as starting materials:

  • allylamine, via palladium(II)-assisted cyclization
  • 4-methoxybenzylamine, via a ring-closing-metathesis strategy
  • 3-ethyl-1-(4-methoxybenzyl)-4-methyl-1,5-dihydro-2H-pyrrol-2- one

Properties of 3-Ethyl-4-methyl-3-pyrrolin-2-one

Melting point: 100-104 °C (lit.)
Boiling point: 279.0±23.0 °C(Predicted)
Density  0.977±0.06 g/cm3(Predicted)
storage temp.  Sealed in dry,Room Temperature
solubility  Chloroform (Slightly), Methanol (Slightly)
pka 14.44±0.60(Predicted)
form  powder to crystal
color  White to Almost white
Water Solubility  Slightly soluble in water.
CAS DataBase Reference 766-36-9(CAS DataBase Reference)

Safety information for 3-Ethyl-4-methyl-3-pyrrolin-2-one

Signal word Warning
Pictogram(s)

Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
Precautionary Statement Codes P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P280:Wear protective gloves/protective clothing/eye protection/face protection.

Computed Descriptors for 3-Ethyl-4-methyl-3-pyrrolin-2-one

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