3-Ethoxy-4-methoxybenzaldehyde

Synonym(s):3-Ethoxy-p-anisaldehyde

CAS NO.：1131-52-8
Empirical Formula: C10H12O3
Molecular Weight: 180.2
MDL number: MFCD00010128
EINECS: 642-869-4
SAFETY DATA SHEET (SDS)
Update Date: 2024-07-18 18:48:51

3-Ethoxy-4-methoxybenzaldehyde Structural

What is 3-Ethoxy-4-methoxybenzaldehyde?

Chemical properties

Colorless solid

The Uses of 3-Ethoxy-4-methoxybenzaldehyde

3-Ethoxy-4-methoxybenzaldehyde is used as a pharmaceutical intermediate.

What are the applications of Application

3-Ethoxy-4-methoxybenzaldehyde is a derivatized benzaldehyde compound

What are the applications of Application

3-Ethoxy-4-methoxybenzaldehyde may be used to synthesize Compound of Designation red 10 binding (CDr10b) to investigate its role in neuroinflammatory diseases.

Synthesis

In a 3 L dry reaction flask, 157 g of sodium hydroxide was dissolved in 1500 ml of water, 500 g of isovanillin, 120 g of tetrabutylammonium fluoride, and 537 g of ethyl bromide were added, and the reaction was stirred at 25°C for 4 hours. After filtration by suction, an off-white solid powder of 3-ethoxy-4-methoxybenzaldehyde was obtained with a purity of 99.9% and a yield of 96.1%.

General Description

3-Ethoxy-4-methoxybenzaldehyde is a derivative of vanillin.

Properties of 3-Ethoxy-4-methoxybenzaldehyde

Melting point:	51 °C
Boiling point:	155°C/10mmHg(lit.)
Density	1.088±0.06 g/cm3(Predicted)
Flash point:	113 °C
storage temp.	room temp
solubility	Soluble in methanol.
form	powder to crystal
color	White to Orange to Green
Sensitive	Air Sensitive
CAS DataBase Reference	1131-52-8(CAS DataBase Reference)

Safety information for 3-Ethoxy-4-methoxybenzaldehyde

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.