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HomeProduct name list3'-DEOXYADENOSINE 5'-TRIPHOSPHATE SODIUM SALT

3'-DEOXYADENOSINE 5'-TRIPHOSPHATE SODIUM SALT

Synonym(s):3′-dATP;3′-Deoxyadenosine 5′-triphosphate;3′-deoxy-ATP

3'-DEOXYADENOSINE 5'-TRIPHOSPHATE SODIUM SALT Structural

What is 3'-DEOXYADENOSINE 5'-TRIPHOSPHATE SODIUM SALT?

The Uses of 3'-DEOXYADENOSINE 5'-TRIPHOSPHATE SODIUM SALT

Cordycepin 5′-triphosphate sodium salt has been used:

  • as a transcriptional inhibitor in RNA decay assay
  • to inhibit polyadenylation in HEK293T cells before harvesting for in- vitro interaction studies through co-immunoprecipitation (co-Ips)
  • as a positive control in in vitro assays for polymerase inhibition
  • as a precursor to produce cordycepin monophosphate

What are the applications of Application

Cordycepin 5′-triphosphate sodium salt is used for 3′-end labeling of RNA

Definition

ChEBI: Cordycepin triphosphate is a purine ribonucleoside 5'-triphosphate. It has a role as an antimetabolite, an antifungal agent, an antineoplastic agent and an antiviral agent. It is functionally related to a cordycepin.

General Description

Cordycepin (3′-deoxyadenosine) is a cytotoxic adenosine analog and a bioactive agent extracted from Cordyceps militaris. Cordycepin 5′-triphosphate is a toxic derivative of cordycepin.

Biochem/physiol Actions

Cordycepin exhibits various metabolic effects by activating AMP-activated protein kinase (AMPK) in humans. Cordycepin triphosphate inhibits picornavirus polymerase-specific RNA synthesis by blocking in vitro [3H]GMP incorporation. It also retards cell growth by inhibiting RNA synthesis.

Properties of 3'-DEOXYADENOSINE 5'-TRIPHOSPHATE SODIUM SALT

storage temp.  -20°C

Safety information for 3'-DEOXYADENOSINE 5'-TRIPHOSPHATE SODIUM SALT

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
ghs
Health Hazard
GHS08
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
H351:Carcinogenicity
Precautionary Statement Codes P202:Do not handle until all safety precautions have been read and understood.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313:IF exposed or concerned: Get medical advice/attention.

Computed Descriptors for 3'-DEOXYADENOSINE 5'-TRIPHOSPHATE SODIUM SALT

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