3'-DEOXYADENOSINE 5'-TRIPHOSPHATE SODIUM SALT
Synonym(s):3′-dATP;3′-Deoxyadenosine 5′-triphosphate;3′-deoxy-ATP
- CAS NO.:71997-32-5
- Empirical Formula: C10H17N5NaO12P3
- Molecular Weight: 515.18
- MDL number: MFCD32067416
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-04 17:34:41
What is 3'-DEOXYADENOSINE 5'-TRIPHOSPHATE SODIUM SALT?
The Uses of 3'-DEOXYADENOSINE 5'-TRIPHOSPHATE SODIUM SALT
Cordycepin 5′-triphosphate sodium salt has been used:
- as a transcriptional inhibitor in RNA decay assay
- to inhibit polyadenylation in HEK293T cells before harvesting for in- vitro interaction studies through co-immunoprecipitation (co-Ips)
- as a positive control in in vitro assays for polymerase inhibition
- as a precursor to produce cordycepin monophosphate
What are the applications of Application
Cordycepin 5′-triphosphate sodium salt is used for 3′-end labeling of RNA
Definition
ChEBI: Cordycepin triphosphate is a purine ribonucleoside 5'-triphosphate. It has a role as an antimetabolite, an antifungal agent, an antineoplastic agent and an antiviral agent. It is functionally related to a cordycepin.
General Description
Cordycepin (3′-deoxyadenosine) is a cytotoxic adenosine analog and a bioactive agent extracted from Cordyceps militaris. Cordycepin 5′-triphosphate is a toxic derivative of cordycepin.
Biochem/physiol Actions
Cordycepin exhibits various metabolic effects by activating AMP-activated protein kinase (AMPK) in humans. Cordycepin triphosphate inhibits picornavirus polymerase-specific RNA synthesis by blocking in vitro [3H]GMP incorporation. It also retards cell growth by inhibiting RNA synthesis.
Properties of 3'-DEOXYADENOSINE 5'-TRIPHOSPHATE SODIUM SALT
storage temp. | -20°C |
Safety information for 3'-DEOXYADENOSINE 5'-TRIPHOSPHATE SODIUM SALT
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 Health Hazard GHS08 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H351:Carcinogenicity |
Precautionary Statement Codes |
P202:Do not handle until all safety precautions have been read and understood. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P308+P313:IF exposed or concerned: Get medical advice/attention. |
Computed Descriptors for 3'-DEOXYADENOSINE 5'-TRIPHOSPHATE SODIUM SALT
New Products
ALUMINIUM IODIDE 100 GM BUFFER CAPSULE PH 7.0 - 10 CAP BUFFER SOLUTION PH 9.5 (BORATE) EZEE BLUE GEL STAINER BORAX CARMINE (GRENACHERS ALCOHOLIC) POTASSIUM IODATE - IODIDE SOLN 0.1 N Dabigatran Acyl-O3-D-Glucuronide Trifluoroacetic Acid Salt Isofolic Acid Dabigatran 2-O-acylglucuronide metabolite Dabigatran Acyl-?-D- glucuronide Trifluroacetic Acid Erythromycin EP Impurity A Desloratidine Related Compound ARelated products of tetrahydrofuran
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