3-Chloro-2,4,5,6-tetrafluoropyridine

CAS NO.：1735-84-8
Empirical Formula: C5ClF4N
Molecular Weight: 185.51
MDL number: MFCD00010624
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is 3-Chloro-2,4,5,6-tetrafluoropyridine?

Chemical properties

CLEAR COLOURLESS LIQUID

General Description

3-Chloro-2,4,5,6-tetrafluoropyridine (3-chlorotetrafluoropyridine) is a fluoropyridine derivative. Its quantum mechanical calculations of energies, geometries and vibrational wave numbers have been performed by DFT level of theory. The interpretation of its FT-IR and FT-Raman spectra have been reported. It forms corresponding organo-zinc compound by reacting with zinc. 3-Chlorotetrafluoropyridine reacts with tris(diethylamino)phosphine (P(NEt)₃) in the presence of a proton donor to form product with fluorine replaced by hydrogen at position 4.

Properties of 3-Chloro-2,4,5,6-tetrafluoropyridine

Boiling point:	118-121 °C (lit.)
Density	1.609 g/mL at 25 °C (lit.)
refractive index	n20/D 1.436(lit.)
Flash point:	>230 °F
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
form	clear liquid
pka	-11.94±0.28(Predicted)
Specific Gravity	1.641
color	Colorless to Almost colorless
BRN	475873
CAS DataBase Reference	1735-84-8(CAS DataBase Reference)
NIST Chemistry Reference	Pyridine, 3-chloro-2,4,5,6-tetrafluoro-(1735-84-8)

Safety information for 3-Chloro-2,4,5,6-tetrafluoropyridine

Signal word	Warning
Pictogram(s)	Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H312:Acute toxicity,dermal H314:Skin corrosion/irritation H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H319:Serious eye damage/eye irritation H332:Acute toxicity,inhalation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P310:Immediately call a POISON CENTER or doctor/physician. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.