3-Butyn-2-one

CAS NO.：1423-60-5
Empirical Formula: C4H4O
Molecular Weight: 68.07
MDL number: MFCD00008775
EINECS: 215-834-2
SAFETY DATA SHEET (SDS)
Update Date: 2023-05-09 09:30:58

What is 3-Butyn-2-one?

Chemical properties

clear yellow to orange-brown liquid

Chemical properties

3-Butyn-2-one is a clear, colorless liquid that is chemically reactive. It has a boiling point of 85.0°C. The autoignition temperature for 3-butyn-2-one is 274°C. 3-Butyn-2-one has a penetrating odor and is a lacrimator. 3-Butyn-2-one has a penetrating odor and is a lacrimator.

The Uses of 3-Butyn-2-one

3-Butyn-2-one was used in the synthesis of clerodane diterpenoid (+/-)-sacacarin. It was used as substrate in stereoselective, conjugate arylation mediated by gallium(III) chloride leading to (E)-α,β-unsaturated ketones.

Definition

ChEBI: Butyn-2-one is a methyl ketone and a terminal acetylenic compound. It is functionally related to a butan-2-one.

General Description

3-Butyn-2-one undergoes asymmetric double-Michael reaction with ortho-tosylamidophenyl malonate catalyzed by chiral aminophosphines to yield indolines. It undergoes double Michael reaction with nitrogen-containing tethered diacid to give pipecolic acid derivatives.

Properties of 3-Butyn-2-one

Boiling point:	85 °C(lit.)
Density	0.87 g/mL at 25 °C(lit.)
refractive index	n20/D 1.406(lit.)
Flash point:	28 °F
storage temp.	0-6°C
form	Liquid
color	Clear yellow to orange-brown
Specific Gravity	0.870
Water Solubility	It is soluble in water.
BRN	605353
CAS DataBase Reference	1423-60-5(CAS DataBase Reference)
NIST Chemistry Reference	3-Butyn-2-one(1423-60-5)
EPA Substance Registry System	3-Butyn-2-one (1423-60-5)

Safety information for 3-Butyn-2-one

Signal word	Danger
Pictogram(s)	Flame Flammables GHS02 Skull and Crossbones Acute Toxicity GHS06
GHS Hazard Statements	H225:Flammable liquids H300:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.