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HomeProduct name list(3-BROMOPROPOXY)-TERT-BUTYLDIMETHYLSILANE

(3-BROMOPROPOXY)-TERT-BUTYLDIMETHYLSILANE

(3-BROMOPROPOXY)-TERT-BUTYLDIMETHYLSILANE Structural

What is (3-BROMOPROPOXY)-TERT-BUTYLDIMETHYLSILANE?

The Uses of (3-BROMOPROPOXY)-TERT-BUTYLDIMETHYLSILANE

(3-Bromopropoxy)-tert-butyldimethylsilane is a reagent in the preparation of piperidinylcarbonyl sulfamates as a novel class of antihyperlipidemic agents with LDL-receptor up-regulation via the adaptor protein autosomal recessive hypercholesterolemia.

The Uses of (3-BROMOPROPOXY)-TERT-BUTYLDIMETHYLSILANE

The propanol functionality of this versatile reagent can be introduced to many pharmaceuticals.1,2,3,4

The Uses of (3-BROMOPROPOXY)-TERT-BUTYLDIMETHYLSILANE

(3-Bromopropoxy)-tert-butyldimethylsilane may be used to introduce propanol functionality to many pharmaceuticals.
It may be used as an alkylating agent in the synthesis of the following:

  • N-[2-[N-[3-(tert-butyldimethylsilyloxy)propyl]-N-ethylamino]ethyl]phthalimide
  • O-(3-tert-butyldimethylsilyloxypropyl)-N-(tert-butoxycarbonyl)-L-tyrosine methyl ester
  • tert-butyldimethyl-[3-(3-methyl-2-nitrophenoxy)propoxy]silane

What are the applications of Application

(3-Bromopropoxy)-tert-butyldimethylsilane is a versatile reagent

General Description

(3-Bromopropoxy)-tert-butyldimethylsilane is a bromo silyl ether.

Properties of (3-BROMOPROPOXY)-TERT-BUTYLDIMETHYLSILANE

Boiling point: 182 °C(lit.)
Density  1.093 g/mL at 25 °C(lit.)
refractive index  n20/D 1.451(lit.)
Flash point: 185 °F
storage temp.  2-8°C
solubility  Chloroform (Sparingly)
form  Oil
color  Colourless

Safety information for (3-BROMOPROPOXY)-TERT-BUTYLDIMETHYLSILANE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for (3-BROMOPROPOXY)-TERT-BUTYLDIMETHYLSILANE

InChIKey QGMROEZDWJTIDW-UHFFFAOYSA-N

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