3-BROMO-7-NITROINDAZOLE
- CAS NO.：74209-34-0
- Empirical Formula: C7H4BrN3O2
- Molecular Weight: 242.03
- MDL number: MFCD00159910
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-11 20:33:26
What is 3-BROMO-7-NITROINDAZOLE?
Chemical properties
Yellow Crystals
The Uses of 3-BROMO-7-NITROINDAZOLE
A more potent inhibitor of rat cerebellar nitric oxide synthase than 7-nitroindazole
The Uses of 3-BROMO-7-NITROINDAZOLE
Inhibitor of nitric oxide synthase (NOS)
The Uses of 3-BROMO-7-NITROINDAZOLE
3-Bromo-7-nitroindazole is a potent and selective neuronal nitric oxide synthase (nNOS) inhibitor (1,2). It is also a neuroprotective compound that inhibits the endoplasmic reticulum stress pathway. 3-Bromo-7-nitroindazole has been used to study the role of nitric oxide synthase (nNOS) in spatial memory formation in rats (2).
What are the applications of Application
3-Bromo-7-nitroindazole is a selective inhibitor of NOS1 and NOS3
storage
Desiccate at +4°C
Properties of 3-BROMO-7-NITROINDAZOLE
| Melting point: | 175-185 °C |
| Boiling point: | 182°C |
| Density | 1.8856 (rough estimate) |
| refractive index | 1.6200 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| solubility | ethanol: 25 mg/mL |
| form | powder |
| pka | 7.85±0.40(Predicted) |
| color | light yellow |
| Sensitive | Light Sensitive |
| CAS DataBase Reference | 74209-34-0(CAS DataBase Reference) |
Safety information for 3-BROMO-7-NITROINDAZOLE
| Signal word | Danger |
| Pictogram(s) |
 Health Hazard GHS08 |
| GHS Hazard Statements |
H360:Reproductive toxicity |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P202:Do not handle until all safety precautions have been read and understood. P280:Wear protective gloves/protective clothing/eye protection/face protection. P308+P313:IF exposed or concerned: Get medical advice/attention. P405:Store locked up. |
Computed Descriptors for 3-BROMO-7-NITROINDAZOLE
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