5-Bromo-2-(trifluoromethoxy)aniline
- CAS NO.:886762-08-9
- Empirical Formula: C7H5BrF3NO
- Molecular Weight: 256.02
- MDL number: MFCD04039242
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
![5-Bromo-2-(trifluoromethoxy)aniline Structural](https://img.chemicalbook.in/CAS/GIF/886762-08-9.gif)
What is 5-Bromo-2-(trifluoromethoxy)aniline?
Description
5-Bromo-2-(trifluoromethoxy)aniline has a wide range of applications in scientific research. It is used as a reagent in organic synthesis and as a catalyst in polymerization reactions. It is also used as a building block for the synthesis of other organic compounds, such as pharmaceuticals and agrochemicals. It is also used in the synthesis of heterocyclic compounds and in the preparation of metal complexes.
The Uses of 5-Bromo-2-(trifluoromethoxy)aniline
5-Bromo-2-(trifluoromethoxy)aniline (5-BTA) is a drug with inhibitory activity against cell proliferation and has been shown to be effective in inhibiting the growth of certain cancer cells, such as those expressing tyrosine kinase isoforms. 5-BTA is also capable of blocking cell proliferation through inhibition of other enzymes (e.g., protein kinases). The oral Bioavailability of 5-BTA has been demonstrated in rats and mice. A2780 cells are human lung cancer cells with mutations in the gene encoding tyrosine kinase. Selectivity for tyrosine kinase isoforms was observed in vitro and in vivo.
Properties of 5-Bromo-2-(trifluoromethoxy)aniline
Boiling point: | 230.2±35.0 °C(Predicted) |
Density | 1.726±0.06 g/cm3(Predicted) |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
pka | 1.38±0.10(Predicted) |
color | Pale yellow |
Safety information for 5-Bromo-2-(trifluoromethoxy)aniline
Signal word | Danger |
Pictogram(s) |
![]() Skull and Crossbones Acute Toxicity GHS06 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for 5-Bromo-2-(trifluoromethoxy)aniline
5-Bromo-2-(trifluoromethoxy)aniline manufacturer
JSK Chemicals
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