(2S,3S,4R,5R,6R)-6-[[[(2S,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-3,4,5-trihydroxy-oxane-2-carboxylic
- CAS NO.:2616-64-0
- Empirical Formula: C15H22N2O18P2
- Molecular Weight: 580.28
- MDL number: MFCD15145135
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-05-22 17:52:39
What is (2S,3S,4R,5R,6R)-6-[[[(2S,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-3,4,5-trihydroxy-oxane-2-carboxylic?
Description
An intermediate in the phase II reaction that results in the formation of glucuro_x0002_nic acid conjugates of xenobiotics which contain substituents such as hydroxyl, amino, or sulfhydryl groups, forming the O-, N-, and S-glucuronides, respectively. UDPGA is formed by two reactions: (i) the formation of UDPG from UTP and glucose 1-phosphate and (ii) the formation of UDPGA from UDPG. The two reactions are catalyzed by UDPG pyrophosphorylase and UDPG dehydrogenase, respectively, whereas glucuronide formation is catalyzed by glucuronosyltransferase. Glucuronide formation from xenobiotics is common in all animal groups except insects.
Definition
ChEBI: A UDP-sugar having alpha-D-glucuronic acid as the sugar component.
Properties of (2S,3S,4R,5R,6R)-6-[[[(2S,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-3,4,5-trihydroxy-oxane-2-carboxylic
Density | 2.05±0.1 g/cm3(Predicted) |
pka | 1.10±0.50(Predicted) |
CAS DataBase Reference | 2616-64-0 |
Safety information for (2S,3S,4R,5R,6R)-6-[[[(2S,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-3,4,5-trihydroxy-oxane-2-carboxylic
Computed Descriptors for (2S,3S,4R,5R,6R)-6-[[[(2S,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-3,4,5-trihydroxy-oxane-2-carboxylic
New Products
(R)-tert-butyl (4-methyl-1-oxopentan-3-yl)carbamate Tubulysin M Tubulysin H Tubulysin E 2,2,6,6-tetramethyl-2H-3,5,6-trihydropyran-4-one 2,2-Difluoropropanol (S)-(+)-3-HYDROXYTETRAHYDROFURAN 1,2,3,6-TETRAHYDROPYRIDINE HYDROCHLORIDE 1-Boc-5-broMo-1H-pyrazolo[3,4-b]pyridine (S)-3-Aminobutanenitrile hydrochloride N-(2-methoxy-5-nitrophenyl)acetamide 5-Nitrobarbituric acid N-[2-(Acetylthio)-1-oxobutyl]glycine ethyl ester 4-chloro-2-hydroxy-5-nitropyridine methyl 2-bromobenzoate 5-Bromo-2-chloroisonicotinic acid 1H-Imidazole-4-carbonitrile 7-Methoxyquinoline-4-carboxylic acid 7-Methoxyquinoline-4-carbonitrile (2R,3S)-2-Azido-3-methylpentanoic acid (2S)-3-Methyl-2-(methylamino)-1-butanol FUSIDIC ACID EP IMPURITY H / FUSIDIC ACID BP IMPURITY H / 11-KETO FUSIDIC ACID Sertraline EP Impurity C / Sertraline BP Impurity C / rac-cis-3-Dechloro Sertraline HCl Montelukast (3S)-Hydroxy BenzoateRelated products of tetrahydrofuran
Uridine 5'-(trihydrogen diphosphate), mono-alpha-d-glucopyranosyl ester
D-Galactose
L(+)-Rhamnose monohydrate
D-Glucaric acid
L-Arabinopyranose
L-Arabinose
α-L-Rhamnopyranose monohydrate
D-Glucuronic acid
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