(2S,3S,4R,5R,6R)-6-[[[(2S,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-3,4,5-trihydroxy-oxane-2-carboxylic

CAS NO.：2616-64-0
Empirical Formula: C15H22N2O18P2
Molecular Weight: 580.29
MDL number: MFCD15145135
SAFETY DATA SHEET (SDS)
Update Date: 2025-03-21 14:41:48

What is (2S,3S,4R,5R,6R)-6-[[[(2S,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-3,4,5-trihydroxy-oxane-2-carboxylic?

Description

An intermediate in the phase II reaction that results in the formation of glucuro_x0002_nic acid conjugates of xenobiotics which contain substituents such as hydroxyl, amino, or sulfhydryl groups, forming the O-, N-, and S-glucuronides, respectively. UDPGA is formed by two reactions: (i) the formation of UDPG from UTP and glucose 1-phosphate and (ii) the formation of UDPGA from UDPG. The two reactions are catalyzed by UDPG pyrophosphorylase and UDPG dehydrogenase, respectively, whereas glucuronide formation is catalyzed by glucuronosyltransferase. Glucuronide formation from xenobiotics is common in all animal groups except insects.

Definition

ChEBI: A UDP-sugar having alpha-D-glucuronic acid as the sugar component.

Properties of (2S,3S,4R,5R,6R)-6-[[[(2S,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-3,4,5-trihydroxy-oxane-2-carboxylic

Density	2.05±0.1 g/cm3(Predicted)
pka	1.10±0.50(Predicted)
CAS DataBase Reference	2616-64-0

Safety information for (2S,3S,4R,5R,6R)-6-[[[(2S,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-3,4,5-trihydroxy-oxane-2-carboxylic

Computed Descriptors for (2S,3S,4R,5R,6R)-6-[[[(2S,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-3,4,5-trihydroxy-oxane-2-carboxylic

New Products

Tetrabutylammonium hydrogen sulfate 2,2,6-Trimethyl-4H-1,3-dioxin-4-one 4-Piperidinopiperidine tert-Butyl acetoacetate 4-BROMOMETHYLTETRAHYDROPYRAN 3-Hydroxyazetidine hydrochloride Diallylamine, 99% Calcium hydroxide, 95% Aluminum oxide, basic 2-Bromophenylacetonitrile, 97% L-tert-Leucine,97% N-Hydroxy-2-methylpropanimidamide 4-(3,4-Dichlorophenyl)-3,4-Dihydro-N-Methyl-1-(2H)-Naphthalenimine (Schiff Base) 2-AMINO-3,5-DIBROMO BENZALDEHYDE [ADBA] L-Glutamic Acid Dimethyl Ester Hcl 10-Methoxy-5H-dibenz[b,f]azepine 5-Cyanophthalide N, N-Carbonyldiimidazole (CDI) 3-Methoxybenzonitrile 4-Methoxybenzonitrile Dibenzoyl Peroxide Titanium Dioxide Chloral Pentachlorobenzonitrile

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Uridine 5'-(trihydrogen diphosphate), mono-alpha-d-glucopyranosyl ester

D-Galactose

L(+)-Rhamnose monohydrate

D-Glucaric acid

L-Arabinopyranose

L-Arabinose

α-L-Rhamnopyranose monohydrate

D-Glucuronic acid