Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name list(2'S)-Nicotine 1-Oxide

(2'S)-Nicotine 1-Oxide

(2'S)-Nicotine 1-Oxide Structural

What is (2'S)-Nicotine 1-Oxide?

Description

(2''S)-Nicotine-1-oxide is a metabolite of nicotine . It is formed when nicotine is metabolized in the liver by cytochrome P450 (CYP) isoform CYP2A6. (2''S)-Nicotine-1-oxide has been detected in human sperm and semen.

Chemical properties

Light Yellow Crystals

The Uses of (2'S)-Nicotine 1-Oxide

Nicotine-1’-N-oxide is a derivative of Nicotine (N412420) found in the leaves, stems, and roots of N. tabacum, N. affinis and N. sylvestris. Nicotine-1’-N-oxide has also been identified as metabolites of nicotine in animals and in man. The metabolism of nicotine in man proceeds by alternative routes of oxidation of nitrogen to form nicotine-1’-N-oxide (both diastereomers) or cotinine. The ratio of these two products has been suggested as an indicator of bladder cancer in humans.

The Uses of (2'S)-Nicotine 1-Oxide

Nicotine-1’-N-oxide is a derivative of nicotine found in the leaves, stems, and roots of N. tabacum, N. affinis and N. sylvestris. Nicotine-1’-N-oxide has also been identified as metabolites of nicotine in animals and in man. The metabolism of nicotine i

Definition

ChEBI: A member of the class of pyridine N-oxides obtained by oxidation of the pyridine nitrogen of (S)-nicotine.

Properties of (2'S)-Nicotine 1-Oxide

Boiling point: 347.9±30.0 °C(Predicted)
Density  1.15±0.1 g/cm3(Predicted)
storage temp.  Refrigerator, Under Inert Atmosphere
solubility  DMF: 50 mg/mL; DMSO: 30 mg/mL; Ethanol: 50 mg/mL; PBS (pH 7.2): 1 mg/mL
form  A crystalline solid
pka 8.79±0.40(Predicted)
Stability: Very Hygroscopic
CAS DataBase Reference 2820-55-5

Safety information for (2'S)-Nicotine 1-Oxide

Computed Descriptors for (2'S)-Nicotine 1-Oxide

Related products of tetrahydrofuran

You may like

Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.