2,6-Dinitroaniline

CAS NO.：606-22-4
Empirical Formula: C6H5N3O4
Molecular Weight: 183.12
MDL number: MFCD00007148
EINECS: 210-108-1
SAFETY DATA SHEET (SDS)
Update Date: 2023-10-21 09:05:36

What is 2,6-Dinitroaniline?

Chemical properties

orange-brown crystalline powder

The Uses of 2,6-Dinitroaniline

2,6-Dinitroaniline is used for organic synthesis intermediates, dyes intermediates, used in the preparation of 2,6-dinitroiodobenzene. It act as a precursor for various new 1,2,3-trisubstituted halobenzene derivatives.

Production Methods

Chlorobenzene-4-sulfonic acid is dinitrated to give 4- chloro-3,5-dinitrobenzenesulfonic acid [88-91-5], which is desulfonated by heating the diluted sulfuric acid solution from the nitration mix to give 2- chloro-1,3- dinitrobenzene [606-21-3]; the latter is aminated to 2,6-Dinitroaniline.

General Description

2,6-Dinitroaniline is a dinitroaniline. It serves as precursor to various new 1,2,3-trisubstituted halobenzene derivatives.

Purification Methods

Purify the nitroaniline by chromatography on alumina, then crystallise it from *benzene or EtOH. The N-acetyl derivative has m 197o (from EtOH). [Beilstein 12 IV 1729.]

Properties of 2,6-Dinitroaniline

Melting point:	134 °C (dec.) (lit.)
Boiling point:	316.77°C (rough estimate)
Density	1.6188 (rough estimate)
refractive index	1.6910 (estimate)
storage temp.	Store below +30°C.
form	Crystalline Powder or Crystals
pka	pK1:-5.23(+1) (25°C)
color	White to off-white
Water Solubility	practically insoluble
Merck	14,3271
BRN	2214886
CAS DataBase Reference	606-22-4(CAS DataBase Reference)
NIST Chemistry Reference	Benzenamine, 2,6-dinitro-(606-22-4)

Safety information for 2,6-Dinitroaniline

Signal word	Danger
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08 Environment GHS09
GHS Hazard Statements	H373:Specific target organ toxicity, repeated exposure H411:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P262:Do not get in eyes, on skin, or on clothing. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P314:Get medical advice/attention if you feel unwell.