2,6-DICHLORO-5-FLUORONICOTINAMIDE
- CAS NO.:113237-20-0
- Empirical Formula: C6H3Cl2FN2O
- Molecular Weight: 209.01
- MDL number: MFCD01571365
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-04-24 17:21:40
What is 2,6-DICHLORO-5-FLUORONICOTINAMIDE?
The Uses of 2,6-DICHLORO-5-FLUORONICOTINAMIDE
2,6-Dichloro-5-fluoronicotinamide is a fluorinated pharmaceutical intermediate compound used in the synthesis of Sotorasib and AMG 510. Sotorasib is a RAS GTPase family inhibitor used for the treatment of KRAS-mutated solid tumours including non-small cell lung cancer (NSCLC) and colorectal cancer.
Properties of 2,6-DICHLORO-5-FLUORONICOTINAMIDE
Melting point: | 160-162 |
Boiling point: | 259.0±40.0 °C(Predicted) |
Density | 1.614±0.06 g/cm3(Predicted) |
storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
pka | 13.36±0.50(Predicted) |
form | crystalline solid |
color | White |
InChI | InChI=1S/C6H3Cl2FN2O/c7-4-2(6(10)12)1-3(9)5(8)11-4/h1H,(H2,10,12) |
Safety information for 2,6-DICHLORO-5-FLUORONICOTINAMIDE
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for 2,6-DICHLORO-5-FLUORONICOTINAMIDE
InChIKey | ZVYNUGSPFZCYEV-UHFFFAOYSA-N |
SMILES | C1(Cl)=NC(Cl)=C(F)C=C1C(N)=O |
Abamectin manufacturer
Shiv pharma chem
1Y
Phone:+91-9974421207
Whatsapp: +91 9974421207
product: 113237-20-0 2,6 di chloro - 5 fluoronicotinamide 98%
New Products
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Formamide
2,6-DICHLORO-5-FLUORO-N-(2-THIENYLMETHYL)NICOTINAMIDE
2,6-DICHLORO-5-FLUORO-N-(2-FURYLMETHYL)NICOTINAMIDE
2,6-DICHLORO-5-FLUORO-N-PYRIDIN-3-YLNICOTINAMIDE
2,6-DICHLORO-5-FLUORO-N-[3-(TRIFLUOROMETHYL)PHENYL]NICOTINAMIDE
(2,6-DICHLORO-5-FLUOROPYRIDIN-3-YL)(MORPHOLINO)METHANONE
(2,6-DICHLORO-5-FLUOROPYRIDIN-3-YL)(PIPERIDINO)METHANONE
2,6-DICHLORO-5-FLUORONICOTINAMIDE
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