2,6-Bis[(4R)-4-phenyl-2-oxazolinyl]pyridine
Synonym(s):(R,R)-2,6-Bis(4,5-dihydro-4-phenyl-2-oxazolyl)pyridine;(R,R)-2,6-Bis(4-phenyl-2-oxazolinyl)pyridine
- CAS NO.:128249-70-7
- Empirical Formula: C23H19N3O2
- Molecular Weight: 369.42
- MDL number: MFCD01863585
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-12 17:17:06
What is 2,6-Bis[(4R)-4-phenyl-2-oxazolinyl]pyridine?
Chemical properties
White needles
The Uses of 2,6-Bis[(4R)-4-phenyl-2-oxazolinyl]pyridine
2,6-Bis[(4R)-4-phenyl-2-oxazolinyl]pyridine [Pybox] may be used as a chiral ligand in the copper-catalyzed enatioselective arylation of N-arylated tetrahydroisoquinolines (THIQs) with arylboronic acids in the presence of a photoredox catalyst.
Properties of 2,6-Bis[(4R)-4-phenyl-2-oxazolinyl]pyridine
Melting point: | 171-175 °C(lit.) |
Boiling point: | 600.4±55.0 °C(Predicted) |
alpha | 185 º (c=1, methylene chloride) |
Density | 1.28±0.1 g/cm3(Predicted) |
storage temp. | Inert atmosphere,Room Temperature |
form | crystal |
pka | 3.07±0.70(Predicted) |
color | white |
optical activity | [α]22/D 187°, c = 1 in methylene chloride |
Water Solubility | Insoluble |
CAS DataBase Reference | 128249-70-7(CAS DataBase Reference) |
Safety information for 2,6-Bis[(4R)-4-phenyl-2-oxazolinyl]pyridine
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2,6-Bis[(4R)-4-phenyl-2-oxazolinyl]pyridine
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Pyridine
PHENYL VALERATE
Diphenyl ether
Fenoxaprop-P
Phenyl salicylate
Phenylacetic acid
4-Phenylpyridine
PHENYL RESIN
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