2,4,6-Trichloroaniline

CAS NO.：634-93-5
Empirical Formula: C6H4Cl3N
Molecular Weight: 196.46
MDL number: MFCD00007663
EINECS: 211-219-8
SAFETY DATA SHEET (SDS)
Update Date: 2024-08-21 22:41:43

What is 2,4,6-Trichloroaniline ?

Chemical properties

fine purple fibres

The Uses of 2,4,6-Trichloroaniline

2,4,6-trichloroaniline is important as an intermediate in the manufacture of benzene derivatives, including 1,3,5-trichlorobenzene and is useful in the formation of fungicides, mono-azo dyestuffs, and the preparation of hexachlorodiphenyl urea.
Tetrachloronitrobenzene was prepared from 2:4:6-trichloroaniline,which was converted by a Sandmeyer reaction into 1:2:3:5- tetrachlorobenzene.

Preparation

2,4,6-Trichloroaniline can be prepared by reaction of dry aniline with chlorine gas while in a anhydrous solution of carbon tetrachloride. 2,4,6-Trichloroaniline precipitates from solution as a white solid. If water is introduced to the solution the white material will polymerize to form aniline black.
Process for the preparation of 2,4,6-trichloroaniline

General Description

Long needles or fine, light purple fibers.

Air & Water Reactions

2,4,6-Trichloroaniline may be sensitive to exposure to light and air. Insoluble in water.

Reactivity Profile

2,4,6-Trichloroaniline is incompatible with acids, acid chlorides, acid anhydrides, chloroformates, and strong oxidizing agents. .

Fire Hazard

Flash point data for 2,4,6-Trichloroaniline are not available. 2,4,6-Trichloroaniline is probably combustible.

Safety Profile

Moderately toxic by ingestion.Irritant. Questionable carcinogen with experimentalcarcinogenic data. Mutation data reported. When heatedto decomposition it emits very toxic fumes of Clí andNOx.

Purification Methods

Crystallise the aniline from ligroin. The benzoyl derivative has m 174o (from EtOH). [Beilstein 12 H 627, 12 IV 1281.]

Properties of 2,4,6-Trichloroaniline

Melting point:	73-75 °C (lit.)
Boiling point:	262 °C (lit.)
Density	1.6807 (rough estimate)
vapor pressure	0-0.631Pa at 25℃
refractive index	1.6300 (estimate)
Flash point:	262°C
storage temp.	Storage temperature: no restrictions.
solubility	0.039g/l slightly soluble
form	neat
pka	0.07±0.10(Predicted)
color	Needles or liquid from pet ether
Water Solubility	<0.1 g/100 mL at 21.5 ºC
BRN	879568
Stability:	Stable, but may be light or air sensitive. Incompatible with acids, acid chlorides, acid anhydrides, chloroformates, strong oxidizing agents.
CAS DataBase Reference	634-93-5(CAS DataBase Reference)
NIST Chemistry Reference	Benzenamine, 2,4,6-trichloro-(634-93-5)
EPA Substance Registry System	2,4,6-Trichloroaniline (634-93-5)

Safety information for 2,4,6-Trichloroaniline

Signal word	Danger
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08 Environment GHS09
GHS Hazard Statements	H301:Acute toxicity,oral H311:Acute toxicity,dermal H331:Acute toxicity,inhalation H373:Specific target organ toxicity, repeated exposure H400:Hazardous to the aquatic environment, acute hazard H410:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P260:Do not breathe dust/fume/gas/mist/vapours/spray. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P311:Call a POISON CENTER or doctor/physician. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P405:Store locked up. P501:Dispose of contents/container to..…