2,4-Thiazolidinedione
- CAS NO.：2295-31-0
- Empirical Formula: C3H3NO2S
- Molecular Weight: 117.13
- MDL number: MFCD00005478
- EINECS: 218-941-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-25 16:21:11
What is 2,4-Thiazolidinedione?
Chemical properties
White to Off-White Powder
The Uses of 2,4-Thiazolidinedione
2,4-Thiazolidinedione may be used in the synthesis of sixteen 5-arylidene-2,4-thiazolidinediones, via ultrasound-promoted aldol condensation reaction. It may be used as starting material for the synthesis of drugs with antihyperglycemic activity.
The Uses of 2,4-Thiazolidinedione
Inhibitor of enzyme
Definition
ChEBI: A thiazolidenedione carrying oxo substituents at positions 2 and 4.
General Description
2,4-Thiazolidinedione is a well-known peroxisome proliferator-activated receptors (PPAR) activator. Its effect on aging process using kidneys from Fischer 344 rats has been reported. A library of conjugates of 2,4-thiazolidinedione has been synthesized by Knoevenagel condensation followed by reduction using hydrogen gas and Pd/C catalyst. Knoevenagel condensation of various aromatic aldehydes with 2,4-thiazolidinedione in polyethylene glycol-300 has been reported.
Flammability and Explosibility
Not classified
Solubility
Soluble in water (30 mg/ml at 3°C), methanol, DMSO, ethanol, and ethyl ether.
Properties of 2,4-Thiazolidinedione
| Melting point: | 125-127 °C (lit.) |
| Boiling point: | 178-179 °C (19 mmHg) |
| Density | 1.408 (estimate) |
| vapor pressure | 0Pa at 25℃ |
| refractive index | 1.5130 (estimate) |
| Flash point: | 178-179°C/19mm |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 6.50±0.10(Predicted) |
| form | Crystalline Powder |
| color | Slightly yellow |
| Water Solubility | Soluble in water (30 mg/ml at 3°C), methanol, DMSO, ethanol, and ethyl ether. |
| BRN | 110700 |
| CAS DataBase Reference | 2295-31-0(CAS DataBase Reference) |
| NIST Chemistry Reference | 2,4-Thiazolidinedione(2295-31-0) |
| EPA Substance Registry System | 2,4-Thiazolidinedione (2295-31-0) |
Safety information for 2,4-Thiazolidinedione
| Signal word | Warning |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H301:Acute toxicity,oral |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P321:Specific treatment (see … on this label). P405:Store locked up. |
Computed Descriptors for 2,4-Thiazolidinedione
| InChIKey | ZOBPZXTWZATXDG-UHFFFAOYSA-N |
Abamectin manufacturer
Shreenath Chemicals
1Y
Phone:+918369634120
Whatsapp: +91 8369634120
product: 2295-31-0 2 , 4 Thiazolidine Dione 98%
KARPSCHEM LABORATORIES PVT. LTD.
1Y
Phone:+917249203006
Whatsapp: +91 7249203006
product: Pioglitazone impurity
thiazolidine-2,4-dione 96%
Vidgas science and technologies Pvt Ltd
1Y
Phone:+919030019844
Whatsapp: +91 9030019844
product: Thiazolidine-2,4-dione 2295-31-0 98%
S S Arofine
1Y
Phone:91-7020384585
Whatsapp: +91-7020384585
product: 2295-31-0 2,4-Thiazolidinedione 98%
Medicina Lyfe Care
1Y
Phone:+91-9687603963
Whatsapp: +91-9687603963
product: 2,4-Thiazolidinedione 2295-31-0 98%
New Products
4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
You may like
-
2295-31-0 2,4-THIAZOLIDINEDIONE 99%View Details
2295-31-0 -
2,4-Thiazolidinedione 2295-31-0 98%View Details
2295-31-0 -
2, 4-Thiazolidinedione CAS 2295-31-0View Details
2295-31-0 -
2,4-Thiazolidinedione, 97% CAS 2295-31-0View Details
2295-31-0 -
2,4-Thiazolidinedione CAS 2295-31-0View Details
2295-31-0 -
2,4 Thiozolidine Dione 99%View Details -
2,4 Thiazolidine Dione CASView Details
-
2,4-Thiazolidinedione CAS 2295-31-0View Details
2295-31-0
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.