2,4-DIFLUOROBENZENESULFONYL CHLORIDE

CAS NO.：13918-92-8
Empirical Formula: C6H3ClF2O2S
Molecular Weight: 212.6
MDL number: MFCD00042481
EINECS: 629-141-1
SAFETY DATA SHEET (SDS)
Update Date: 2023-12-25 13:23:17

What is 2,4-DIFLUOROBENZENESULFONYL CHLORIDE?

Chemical properties

clear colorless to light yellow liquid

The Uses of 2,4-DIFLUOROBENZENESULFONYL CHLORIDE

2,4-Difluorobenzenesulfonyl chloride may be used in the preparation of 2,4-difluoro-N,N-dimethylbenzenesulfonamide, a precursor for poly(aryl ether sulfonamide)s.
It may be used in the preparation of the following benzenesulfonamide quinoline derivatives with potent anti-HIV-1 (human immunodeficiency virus type 1) activity:

2,4-difluoro-N-methyl-N-(quinolin-8-yl)benzenesulfonamide
N-ethyl-2,4-difluoro-N-(quinolin-8-yl)benzenesulfonamide
2,4-difluoro-N-(quinolin-8-yl)benzenesulfonamide

General Description

2,4-Difluorobenzenesulfonyl chloride is an aryl sulfonyl chloride derivative.

Properties of 2,4-DIFLUOROBENZENESULFONYL CHLORIDE

Boiling point:	101-102 °C (1 mmHg)
Density	1.581 g/mL at 25 °C(lit.)
refractive index	1.5187
Flash point:	>110°C
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
form	Liquid
color	Clear colorless to light yellow
Sensitive	Moisture Sensitive
BRN	2970373
CAS DataBase Reference	13918-92-8(CAS DataBase Reference)

Safety information for 2,4-DIFLUOROBENZENESULFONYL CHLORIDE

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05
GHS Hazard Statements	H314:Skin corrosion/irritation
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.