PENTAFLUOROBENZENESULFONYL CHLORIDE

CAS NO.：832-53-1
Empirical Formula: C6ClF5O2S
Molecular Weight: 266.57
MDL number: MFCD00007427
EINECS: 212-620-0
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is PENTAFLUOROBENZENESULFONYL CHLORIDE?

Chemical properties

clear colourless to light yellow liquid

The Uses of PENTAFLUOROBENZENESULFONYL CHLORIDE

Pentafluorobenzenesulfonyl chloride is used as derivatizing reagent for simultaneous determination of fluoxetine and p-trifluoromethylphenol, an O-dealkylated metabolite of fluoxetine in human liver microsomes. It is also used for electrophore labeling of small tyrosyl peptides for their analysis by gas chromatography with electron-capture detection. It is also employed as derivatizing reagent for amphetamine in determination of amphetamine in human plasma samples using gas chromatography with electron-capture detection.

General Description

Pentafluorobenzenesulfonyl chloride reacts with benzene and thiophene derivatives in the presence of a ruthenium (II) catalyst to form corresponding perfluorophenylated compounds.

Biochem/physiol Actions

Pentafluorobenzenesulfonyl chloride is derivatizing reagent for amphetamine in determination of amphetamine in human plasma samples using gas chromatography with electron-capture detectio.

Properties of PENTAFLUOROBENZENESULFONYL CHLORIDE

Boiling point:	210-211 °C(lit.)
Density	1.796 g/mL at 25 °C(lit.)
refractive index	n20/D 1.479(lit.)
Flash point:	195 °F
storage temp.	Sealed in dry,Room Temperature
form	clear liquid
Specific Gravity	1.797
color	Colorless to Almost colorless
Water Solubility	Soluble in water (reacts slowly).
Sensitive	Moisture Sensitive
BRN	2142325
CAS DataBase Reference	832-53-1(CAS DataBase Reference)

Safety information for PENTAFLUOROBENZENESULFONYL CHLORIDE

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05
GHS Hazard Statements	H314:Skin corrosion/irritation
Precautionary Statement Codes	P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.