2,4-Dichlorobenzaldehyde

Synonym(s):2,4-Dichlorobenzaldehyde

CAS NO.：874-42-0
Empirical Formula: C7H4Cl2O
Molecular Weight: 175.01
MDL number: MFCD00003305
EINECS: 212-861-1
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-18 17:43:10

What is 2,4-Dichlorobenzaldehyde?

Chemical properties

light yellow to beige crystalline powder, crystals

The Uses of 2,4-Dichlorobenzaldehyde

2,4-Dichlorobenzaldehyde is used in the synthesis of platelet aggregation inhibitors. Also used in the preparation of novel Schiff bases containing quinazolinone rings.

The Uses of 2,4-Dichlorobenzaldehyde

2,4-Dichlorobenzaldehyde was used in the solid-phase synthesis of a series of indole-based peptoids.

Synthesis Reference(s)

Tetrahedron Letters, 30, p. 3677, 1989 DOI: 10.1016/S0040-4039(01)80481-0

General Description

White crystalline solid or off-white chunky solid with black specks and a pungent odor. Average shelf life 1 year in a closed container.

Air & Water Reactions

Sensitive to light. May also be sensitive to prolonged exposure to air and moisture. Insoluble in water.

Reactivity Profile

2,4-Dichlorobenzaldehyde is incompatible with iron, oxygen and oxygen-containing materials. 2,4-Dichlorobenzaldehyde is also incompatible with strong oxidizers and strong bases.

Fire Hazard

2,4-Dichlorobenzaldehyde is combustible.

Purification Methods

Crystallise the aldehyde from EtOH or ligroin. [Beilstein 7 IV 575.]

Properties of 2,4-Dichlorobenzaldehyde

Melting point:	64-69 °C (lit.)
Boiling point:	233 °C (lit.)
Density	1.3456 (rough estimate)
refractive index	1.5756 (estimate)
Flash point:	135 °C
storage temp.	Store below +30°C.
form	Crystalline Powder, Crystals and/or Chunks
color	Light yellow to beige
Water Solubility	<0.1 g/100 mL at 24 ºC
Sensitive	Air Sensitive
BRN	471601
CAS DataBase Reference	874-42-0(CAS DataBase Reference)
NIST Chemistry Reference	Benzaldehyde, 2,4-dichloro-(874-42-0)
EPA Substance Registry System	Benzaldehyde, 2,4-dichloro- (874-42-0)

Safety information for 2,4-Dichlorobenzaldehyde

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Environment GHS09
GHS Hazard Statements	H314:Skin corrosion/irritation H411:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P260:Do not breathe dust/fume/gas/mist/vapours/spray. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.