2,4-Dibromoaniline
- CAS NO.:615-57-6
- Empirical Formula: C6H5Br2N
- Molecular Weight: 250.92
- MDL number: MFCD00007633
- EINECS: 210-434-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 14:08:57
What is 2,4-Dibromoaniline?
Chemical properties
beige powder
The Uses of 2,4-Dibromoaniline
2,4-Dibromoaniline is used in preparation of glycopeptides and targeted bifunctional degraders.
The Uses of 2,4-Dibromoaniline
2,4-Dibromoaniline can be used as:
- A starting material to synthesize acetylenic amine by reacting with trimethylsilylacetylene, which is used as a ligand to prepare the bis-amido complex of Ti(IV).
- A substrate in the Pd-catalyzed ortho-selective cross-coupling reactions of dihaloarenes with Grignard reagents.
- A reactant to prepare dialkyl-substituted aminoaryl sulfides using a Grignard reagent.
- A starting material to synthesize substituted 2-mercapto benzimidazoles.
Purification Methods
Crystallise the aniline from aqueous EtOH. The picrate has m 124o. [Beilstein 12 H 655, 12 I 326, 12 II 356, 12 III 1471, 12 IV 1532.]
Properties of 2,4-Dibromoaniline
Melting point: | 78-80 °C (lit.) |
Boiling point: | 156 °C (24 mmHg) |
Density | 2.26 |
refractive index | 1.5800 (estimate) |
Flash point: | 156°C/24mm |
storage temp. | Store below +30°C. |
Water Solubility | Insoluble in water |
form | powder to crystal |
pka | 1.83±0.10(Predicted) |
color | White to Light yellow |
BRN | 2206653 |
CAS DataBase Reference | 615-57-6(CAS DataBase Reference) |
NIST Chemistry Reference | Benzenamine, 2,4-dibromo-(615-57-6) |
EPA Substance Registry System | 2,4-Dibromoaniline (615-57-6) |
Safety information for 2,4-Dibromoaniline
Signal word | Danger |
Pictogram(s) |
Skull and Crossbones Acute Toxicity GHS06 |
GHS Hazard Statements |
H301:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2,4-Dibromoaniline
2,4-Dibromoaniline manufacturer
Sintilla Medcoms Pvt Ltd
1Y
Phone:+91-8886733867
Whatsapp: +91 8886733867
product: 2,4-Dibromoaniline 98%
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