1,3-Bis(bromomethyl)benzene

CAS NO.：626-15-3
Empirical Formula: C8H8Br2
Molecular Weight: 263.96
MDL number: MFCD00000178
EINECS: 210-931-6
SAFETY DATA SHEET (SDS)
Update Date: 2025-01-27 09:38:02

What is 1,3-Bis(bromomethyl)benzene?

Chemical properties

white to light yellow crystal powde

The Uses of 1,3-Bis(bromomethyl)benzene

It is used in preparation of four novel dinuclear half-titanocenes with?meta- and?orthoxylene bridges as new metallocenes. It was used in the synthesis of dissymmetrical bis-macro cyclic salt.

The Uses of 1,3-Bis(bromomethyl)benzene

1,3-Bis(bromomethyl)benzene has been used in preparation of four novel dinuclear half-titanocenes with meta - and ortho xylene bridges as new metallocenes 1 . It was used in the synthesis of dissymmetrical bis -macrocyclic salt 2 .

General Description

α,α′-Dibromo-m-xylene can cross-link and cyclize peptides containing two cysteine residues.

Purification Methods

Crystallise it from acetone or *benzene, and fractionally distil it under vacuum. [Wenner Org Chem 17 527 1952, Beilstein 5 H 374, 5 I 184, 5 II 294, 5 III 839, 5 IV 946.]

Properties of 1,3-Bis(bromomethyl)benzene

Melting point:	74-77 °C(lit.)
Boiling point:	135-140 °C20 mm Hg(lit.)
Density	1.9590
refractive index	1.6113 (estimate)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	dioxane: 0.1 g/mL, clear, colorless
form	Crystalline Powder and Chunks
color	White to brown
Water Solubility	Insoluble in water.
BRN	971085
CAS DataBase Reference	626-15-3(CAS DataBase Reference)
NIST Chemistry Reference	Benzene, 1,3-bis(bromomethyl)-(626-15-3)
EPA Substance Registry System	1,3-Bis(bromomethyl)benzene (626-15-3)

Safety information for 1,3-Bis(bromomethyl)benzene

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.