2,3,5-Triiodobenzoic acid
Synonym(s):TIBA
- CAS NO.:88-82-4
- Empirical Formula: C7H3I3O2
- Molecular Weight: 499.81
- MDL number: MFCD00002420
- EINECS: 201-859-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-01 18:09:03
What is 2,3,5-Triiodobenzoic acid?
Chemical properties
beige powder
The Uses of 2,3,5-Triiodobenzoic acid
2,3,5-Triiodobenzoic Acid is a polar auxin transport inhibitor that inhibits and promotes endoreduplication in hypocotyls and cotyledons.
Definition
ChEBI: 2,3,5-triiodobenzoic acid is a member of the class of benzoic acids that is benzoic acid in which the hydrogens at positions 2, 3 and 5 are replaced by iodine atoms. It is an auxin polar transport inhibitor. It has a role as a member of antiauxins. It is an organoiodine compound and a member of benzoic acids.
What are the applications of Application
The 2,3,5-triiodobenzoic acid (TIBA) is a contrast agent used to improve the visualization of pathological tissues using X-ray techniques. 2, 3, 5-Triiodobenzoic Acid (syn: TIBA) is used as a plant growth regulator, defoliant, and agricultural herbicide. Several investigators have shown TIBA to be successful in causing the retention of buds, blooms, and pods of soybeans. Virtually no results have been reported on using TIBA to retain the 30 to 40% flower shed that occurs with cotton[1-2].
Biochem/physiol Actions
2,3,5-Triiodobenzoic acid (TIBA) inhibits the translocation of indole-3-acetic acid transport.TIBA inhibits the colonization of the main root cortex by Laccaria bicolor S238 N and the formation of the Hartig net.
Toxicology
2,3,5-Triiodobenzoic acid induces physiological complications like increase in oxygen reactive species (ROS), and consequently, contrast-induced nephropathies[1].
References
[1] Jéssica Sodré Silva de Abreu, Janaína Fernandes. "The contrast agent 2,3,5-triiodobenzoic acid (TIBA) induces cell death in tumor cells through the generation of reactive oxygen species." Molecular Biology Reports 48.6 (2021): 5199–5207.
[2] Freytag, et al. "Effect of Multiple Applications of 2,3,5-Triiodobenzoic Acid (TIBA) on Yields of Stormproof and Nonstormproof Cotton." Agronomy Journal 65.4(1973):610-610.
Properties of 2,3,5-Triiodobenzoic acid
Melting point: | 220-222 °C (lit.) |
Boiling point: | 456.7±45.0 °C(Predicted) |
Density | 2.7985 (estimate) |
storage temp. | -20°C |
solubility | methanol: soluble5%, hazy, orange to very deep orange (light) |
form | Solid |
pka | 2.16±0.10(Predicted) |
color | Light brown |
Water Solubility | Insoluble in water. |
Sensitive | Light Sensitive |
BRN | 1955088 |
InChI | InChI=1S/C7H3I3O2/c8-3-1-4(7(11)12)6(10)5(9)2-3/h1-2H,(H,11,12) |
CAS DataBase Reference | 88-82-4(CAS DataBase Reference) |
NIST Chemistry Reference | 2,3,5-Triiodobenzoic acid(88-82-4) |
EPA Substance Registry System | 2,3,5-Triiodobenzoic acid (88-82-4) |
Safety information for 2,3,5-Triiodobenzoic acid
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral |
Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P501:Dispose of contents/container to..… |
Computed Descriptors for 2,3,5-Triiodobenzoic acid
InChIKey | ZMZGFLUUZLELNE-UHFFFAOYSA-N |
SMILES | C(O)(=O)C1=CC(I)=CC(I)=C1I |
Abamectin manufacturer
PEE ESS AROMATICS
Horizon
Tulasi Labs
Prayag Pharmachem
Rishabh Intermediates (formerly Porwal Chemicals)
Evershine Drug Product Pvt Ltd
Suryaprabha Pharmachem
Anand Agencies
New Products
4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
You may like
-
88-82-4 99%View Details
88-82-4 -
88-82-4 2,3,5-Triiodobenzoic acid 98%View Details
88-82-4 -
2,3,5-Triiodobenzoic acid CAS 88-82-4View Details
88-82-4 -
2,3,5-Triiodobenzoic Acid CAS 88-82-4View Details
88-82-4 -
2,3,5-Triiodobenzoic acid, GR 99%+ CAS 88-82-4View Details
88-82-4 -
2,3,5-Triiodobenzoic Acid CAS 88-82-4View Details
88-82-4 -
2,3,5-TRIIODOBENZOIC ACID AR CAS 88-82-4View Details
88-82-4 -
2,3,5-Triiodobenzoic acid CAS 88-82-4View Details
88-82-4