2,2'-DITHIOBIS(5-NITROPYRIDINE)
Synonym(s):Bis(5-nitro-2-pyridyl) disulfide;DTNP
- CAS NO.：2127-10-8
- Empirical Formula: C10H6N4O4S2
- Molecular Weight: 310.31
- MDL number: MFCD00006453
- EINECS: 218-344-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is 2,2'-DITHIOBIS(5-NITROPYRIDINE)?
The Uses of 2,2'-DITHIOBIS(5-NITROPYRIDINE)
2,2′-Dithiobis(5-nitropyridine) was employed:
- as cysteine-activating reagent to study the NMR of G protein-coupled receptors
- in the deprotection assays for protected selenocysteine-containing peptides
- for deprotecting p-methoxybenzyl groups and acetamidomethyl groups from the side-chains of cysteine and selenocysteine
- to remove the p-methoxybenzyl protecting group from cysteine and selenocysteine side-chains
What are the applications of Application
2,2′-Dithiobis(5-nitropyridine) is a cysteine-activating reagent and for deprotecting and removing p-methoxybenzyl groups and acetamidomethyl groups
General Description
2,2′-Dithiobis(5-nitropyridine) is an aromatic disulphide.
Properties of 2,2'-DITHIOBIS(5-NITROPYRIDINE)
| Melting point: | 155-157 °C(lit.) |
| Boiling point: | 139°C (rough estimate) |
| Density | 1.6508 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| storage temp. | Store at RT. |
| pka | -2.88±0.29(Predicted) |
| color | Brown |
| BRN | 305413 |
| CAS DataBase Reference | 2127-10-8(CAS DataBase Reference) |
Safety information for 2,2'-DITHIOBIS(5-NITROPYRIDINE)
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2,2'-DITHIOBIS(5-NITROPYRIDINE)
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