2,2-DI-N-PROPYLACETAMIDE

Synonym(s):Dipropylacetamide;2-propyl-pentanamide;2-Propylvaleramide;Depamid;Depamide

CAS NO.：2430-27-5
Empirical Formula: C8H17NO
Molecular Weight: 143.23
MDL number: MFCD00051534
EINECS: 219-394-2
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-08 20:21:46

What is 2,2-DI-N-PROPYLACETAMIDE?

The Uses of 2,2-DI-N-PROPYLACETAMIDE

Antiepileptic; anticonvulsant.

The Uses of 2,2-DI-N-PROPYLACETAMIDE

Valpromide is a reactant used in the synthesis of mutual prodrugs containing bio-cleavable and drug releasable disulfide linkers.

What are the applications of Application

Valpromide is a valproic acid (VPA) derivative that is hydrolyzed rapidly in vivo to VPA

Definition

ChEBI: A fatty amide derived from valproic acid.

Biochem/physiol Actions

Valpromide (VPD) is a derivative of valproic acid (VPA) and is used as an antiepileptic drug. It is hydrolyzed quickly to VPA in vivo, but has intrinsic anticonvulsant activity.

Properties of 2,2-DI-N-PROPYLACETAMIDE

Melting point:	123-125°C
Boiling point:	261.35°C (rough estimate)
Density	0.9636 (rough estimate)
refractive index	1.4614 (estimate)
storage temp.	room temp
solubility	DMSO: >10mg/mL
form	powder
pka	16.76±0.50(Predicted)
color	white to off-white
Water Solubility	Soluble in chloroform, dimethyl sulfoxide and methanol. Insoluble in water.
Merck	14,9914
BRN	1750444
CAS DataBase Reference	2430-27-5(CAS DataBase Reference)

Safety information for 2,2-DI-N-PROPYLACETAMIDE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral
Precautionary Statement Codes	P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P501:Dispose of contents/container to..…