2,2-Bis(3-amino-4-hydroxyphenyl)propane
- CAS NO.:1220-78-6
- Empirical Formula: C15H18N2O2
- Molecular Weight: 258.32
- MDL number: MFCD00437413
- EINECS: 807-962-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-05-23 11:46:28
What is 2,2-Bis(3-amino-4-hydroxyphenyl)propane?
Description
2,2-Bis(3-amino-4-hydroxyphenyl)propane (BAP) is a diamine organic compound that is used in the synthesis of polyimides.
The Uses of 2,2-Bis(3-amino-4-hydroxyphenyl)propane
2,2-bis(4-hydroxy-3-aminophenyl)propane is used as a polyimide intermediate and functional monomer.
Synthesis
Thedinitro compound (2) (10,000 g, 0.0314 mol) was heated to reflux inabsolute ethanol (100 mL) in the presence of wet 10% Pd/C catalyst(0.650 g). Hydrazine monohydrate (20 mL) was then added dropwiseover a period of 30 min, and the reaction was maintained at reflux for24 h. The hot solution was filtered through Celite to eliminate thecatalyst and partially concentrated under reduced pressure. Afterwards,the concentrate was poured into cold distilled water. The crude productwas filtered, washed with water, dried under vacuum and recrystallizedtwice from methanol to give (3). The diamino compound was obtainedas a white powder: yield: 88%; mp. 263 ??C (DSC); Analysis: Calculatedfor C15H18N2O2: C, 69.74%; H, 7.02%; N, 10.84%. Found: C, 69.35%;H, 7.15%; N, 11.02%. 1H NMR (400 MHz, DMSO-d6): |? (ppm); 8.57 (s,1H, OH), 6.43 (d, J=8.1 Hz, 1H, Har), 6.34 (d, J=1.8 Hz, 1H, Har),6.21 (dd, J=8.1 Hz, 1.8 Hz, 1H, Har), 4.23 (s, 2H, NH) 1.37 (s, 3H, CH3f). 13C NMR (100 MHz, DMSO-d6): |? (ppm) 142.4, 141.4, 135.4, 114.4,113.5, 113.4, 40.8, 30.9.
Properties of 2,2-Bis(3-amino-4-hydroxyphenyl)propane
Melting point: | 248-250 °C |
Boiling point: | 471.1±45.0 °C(Predicted) |
Density | 1.265±0.06 g/cm3(Predicted) |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
solubility | soluble in Dimethylformamide |
form | powder to crystal |
pka | 10.62±0.10(Predicted) |
color | White to Yellow to Orange |
CAS DataBase Reference | 1220-78-6(CAS DataBase Reference) |
Safety information for 2,2-Bis(3-amino-4-hydroxyphenyl)propane
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for 2,2-Bis(3-amino-4-hydroxyphenyl)propane
New Products
(R)-3-Aminobutanenitrile Hydrochloride 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION XANTHAN GUM Racecadotril SODIUM VALPROATE Diclofenac Sodium Methylcobalamin (vitamin B12) SODIUM METHYL PARABEN Folic Acid Impurity G Dabigatran Acyl-O2-D-Glucuronide Trifluoroacetic Acid Salt Glycopyrronium Bromide EP Impurity I Eltrombopag N-Oxide Impurity Di-Nitroso Acyclovir Impurity K DLRD N-OxideRelated products of tetrahydrofuran
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