2-Propylpiperidine

CAS NO.：3238-60-6
Empirical Formula: C8H17N
Molecular Weight: 127.23
MDL number: MFCD00056022
EINECS: 221-801-3
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is 2-Propylpiperidine?

Chemical properties

Colorless liquid; darkens on exposure tolight and air; polymerizes; boils at 166°C(330.8°F); melts at -2°C (28.4°F); alkaline, pKa 3.1; density 0.845 at 20°C (68°F);slightly soluble in water and chloroform,readily soluble in most organic solvents.

The Uses of 2-Propylpiperidine

Coniine is present in all parts of the plantpoison hemlock (Conium maculatum). It isthe first alkaloid to be synthesized and structure determined. Because of its high toxicity,its clinical application is very limited.

What are the applications of Application

(±)-Coniine is a toxin found in poison hemlock

Synthesis Reference(s)

Tetrahedron Letters, 26, p. 4633, 1985 DOI: 10.1016/S0040-4039(00)98771-9

Health Hazard

Coniine is a highly toxic alkaloid. Thetoxic symptoms from ingestion are weakness,drowsiness, nausea, vomiting, muscle contraction, and labored breathing. A high dosecan cause convulsions, cyanosis, asphyxia,and death. Chronic ingestion of coniine produced adverse reproductive effects and spe cific developmental abnormalities in cattles.LD50 value, oral (mice): 100 mg/kg.

Properties of 2-Propylpiperidine

Melting point:	-2℃
Boiling point:	56-60 °C(Press: 13 Torr)
Density	0.85 g/mL at 25 °C(lit.)
storage temp.	Sealed in dry,2-8°C
form	liquid
pka	pK1:11.24(+1) (25°C,μ=0.5)
color	, clear colorless to yellow-green
CAS DataBase Reference	3238-60-6(CAS DataBase Reference)

Safety information for 2-Propylpiperidine

Signal word	Danger
Pictogram(s)	Flame Flammables GHS02 Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08
GHS Hazard Statements	H226:Flammable liquids H301:Acute toxicity,oral H311:Acute toxicity,dermal H331:Acute toxicity,inhalation H351:Carcinogenicity
Precautionary Statement Codes	P201:Obtain special instructions before use. P202:Do not handle until all safety precautions have been read and understood. P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P241:Use explosion-proof electrical/ventilating/lighting/…/equipment. P242:Use only non-sparking tools. P243:Take precautionary measures against static discharge. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P281:Use personal protective equipment as required. P311:Call a POISON CENTER or doctor/physician. P312:Call a POISON CENTER or doctor/physician if you feel unwell. P321:Specific treatment (see … on this label). P322:Specific measures (see …on this label). P330:Rinse mouth. P361:Remove/Take off immediately all contaminated clothing. P363:Wash contaminated clothing before reuse. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P302+P352:IF ON SKIN: wash with plenty of soap and water. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P308+P313:IF exposed or concerned: Get medical advice/attention. P370+P378:In case of fire: Use … for extinction. P405:Store locked up. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P403+P235:Store in a well-ventilated place. Keep cool. P501:Dispose of contents/container to..…