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HomeProduct name list2-Phenylethylamine hydrochloride

2-Phenylethylamine hydrochloride

Synonym(s):β-Phenylethylamine hydrochloride;Phenethylamine hydrochloride

  • CAS NO.:156-28-5
  • Empirical Formula: C8H12ClN
  • Molecular Weight: 157.64
  • MDL number: MFCD00012893
  • EINECS: 205-849-2
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-12-18 14:15:30
2-Phenylethylamine hydrochloride Structural

What is 2-Phenylethylamine hydrochloride?

Description

2-Phenethylamine is a natural monoamine alkaloid that acts as neuromodulator in the central nervous system. It stimulates the release of norepinephrine and dopamine and is metabolized by monoamine oxidases as well as other enzymes. This product is intended for forensic and research applications.

Chemical properties

White to Light yellow powder to crystal. soluble in water, alcohol, ether.

The Uses of 2-Phenylethylamine hydrochloride

2-Phenylethylamine hydrochloride is the hydrochloride salt form of 2-Phenylethylamine, which is an biogenic aromatic amine acting as a monoaminergic neuromodulator or a neurotransmitter in the human central nervous system. It is used to CNS stimulant.

Preparation

In a nitrogen environment, add the aliphatic nitro derivatives (0.6 mmol), pinacol borane (3.6 mmol, 6.0 equiv), tetrahydrofuran (2 mL), triethylboron (5 mol%), and potassium tert-butoxide (5 mol %) into a 10 mL sealed tube and then place it in a 100 oil bath with heating and stirring for 24 hours. At the end of the reaction, add 2mL of 1M hydrochloric acid aqueous solution to the reaction solution and stir at room temperature for 6 h. Finally, 2-Phenylethylamine hydrochloride is obtained by filtration.
2-Phenylethylamine hydrochloride

Safety Profile

Poison by skin contact, subcutaneous, and intravenous routes. A human eye irritant. A skin irritant and possible sensitizer. Human systemic effects by ingestion: blood pressure lowering, anorexia. When heated to decomposition it emits very toxic fumes of

Properties of 2-Phenylethylamine hydrochloride

Melting point: 220-222 °C(lit.)
Boiling point: 217 °C
Flash point: 81 °C
storage temp.  Store at -20°C
solubility  DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 25 mg/ml; PBS (pH 7.2): 10 mg/ml
form  Powder or Crystalline Powder
color  White to off-white
Merck  14,6026
BRN  3624163
InChI InChI=1S/C8H11N.ClH/c9-7-6-8-4-2-1-3-5-8;/h1-5H,6-7,9H2;1H
CAS DataBase Reference 156-28-5(CAS DataBase Reference)
NIST Chemistry Reference 2-Phenylethylammonium chloride(156-28-5)
EPA Substance Registry System Benzeneethanamine, hydrochloride (156-28-5)

Safety information for 2-Phenylethylamine hydrochloride

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P270:Do not eat, drink or smoke when using this product.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 2-Phenylethylamine hydrochloride

InChIKey SKHIBNDAFWIOPB-UHFFFAOYSA-N
SMILES C1(CCN)=CC=CC=C1.Cl

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