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HomeProduct name list2-Morpholinoethanol

2-Morpholinoethanol

Synonym(s):2-Morpholinoethanol;4-Morpholineethanol

  • CAS NO.:622-40-2
  • Empirical Formula: C6H13NO2
  • Molecular Weight: 131.17
  • MDL number: MFCD00006180
  • EINECS: 210-734-5
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-09-09 19:09:56
2-Morpholinoethanol Structural

What is 2-Morpholinoethanol?

Chemical properties

2-Morpholinoethanol is a transparent colorless to yellow liquid. It is used as an organic chemical synthesis intermediate.

The Uses of 2-Morpholinoethanol

4-(2-Hydroxyethyl)morpholine is a morphiline derivative used in the preparation of ester prodrugs of naproxen. 4-(2-Hydroxyethyl)morpholine was also shown to induce repair in rat hepatocyte primary cu lture/DNA.

Definition

ChEBI: 2-Morpholinoethanol is a primary alcohol that is ethanol in which one of the methyl hydrogens is replaced by a morpholin-4-yl group. It is a primary alcohol, a tertiary amino compound and a member of morpholines.

Synthesis Reference(s)

The Journal of Organic Chemistry, 52, p. 467, 1987 DOI: 10.1021/jo00379a035

Flammability and Explosibility

Non flammable

Properties of 2-Morpholinoethanol

Melting point: -1 °C
Boiling point: 227 °C757 mm Hg(lit.)
Density  1.083 g/mL at 25 °C(lit.)
vapor pressure  2.44-7Pa at 20-25℃
refractive index  n20/D 1.476(lit.)
Flash point: 211 °F
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
solubility  Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form  Liquid
pka 14.88±0.10(Predicted)
color  Clear colorless to yellow
PH 10.7 (100g/l, H2O, 20℃)
explosive limit 1.5-9.8%(V)
Water Solubility  miscible
BRN  104375
CAS DataBase Reference 622-40-2(CAS DataBase Reference)
NIST Chemistry Reference 4-Morpholineethanol(622-40-2)
EPA Substance Registry System 4-Morpholineethanol (622-40-2)

Safety information for 2-Morpholinoethanol

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H319:Serious eye damage/eye irritation
Precautionary Statement Codes P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313:IF eye irritation persists: Get medical advice/attention.

Computed Descriptors for 2-Morpholinoethanol

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