2-Morpholinoethanol
Synonym(s):2-Morpholinoethanol;4-Morpholineethanol
- CAS NO.：622-40-2
- Empirical Formula: C6H13NO2
- Molecular Weight: 131.17
- MDL number: MFCD00006180
- EINECS: 210-734-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-07-24 18:12:21
What is 2-Morpholinoethanol?
Chemical properties
2-Morpholinoethanol is a transparent colorless to yellow liquid. It is used as an organic chemical synthesis intermediate.
The Uses of 2-Morpholinoethanol
4-(2-Hydroxyethyl)morpholine is a morphiline derivative used in the preparation of ester prodrugs of naproxen. 4-(2-Hydroxyethyl)morpholine was also shown to induce repair in rat hepatocyte primary cu lture/DNA.
Definition
ChEBI: 2-Morpholinoethanol is a primary alcohol that is ethanol in which one of the methyl hydrogens is replaced by a morpholin-4-yl group. It is a primary alcohol, a tertiary amino compound and a member of morpholines.
Synthesis Reference(s)
The Journal of Organic Chemistry, 52, p. 467, 1987 DOI: 10.1021/jo00379a035
Flammability and Explosibility
Non flammable
Properties of 2-Morpholinoethanol
| Melting point: | -1 °C |
| Boiling point: | 227 °C757 mm Hg(lit.) |
| Density | 1.083 g/mL at 25 °C(lit.) |
| vapor pressure | 2.44-7Pa at 20-25℃ |
| refractive index | n |
| Flash point: | 211 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) |
| form | Liquid |
| pka | 14.88±0.10(Predicted) |
| color | Clear colorless to yellow |
| PH | 10.7 (100g/l, H2O, 20℃) |
| explosive limit | 1.5-9.8%(V) |
| Water Solubility | miscible |
| BRN | 104375 |
| CAS DataBase Reference | 622-40-2(CAS DataBase Reference) |
| NIST Chemistry Reference | 4-Morpholineethanol(622-40-2) |
| EPA Substance Registry System | 4-Morpholineethanol (622-40-2) |
Safety information for 2-Morpholinoethanol
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for 2-Morpholinoethanol
2-Morpholinoethanol manufacturer
JSK Chemicals
3Y
Phone:+91-9879767984
Whatsapp: +91-9879767970
product: 622-40-2 4-(2-Hydroxyethyl)morpholine, 99% 99%
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