2-Methylhydroquinone
Synonym(s):2,5-Dihydroxytoluene, Toluhydroquinone;2-Methylhydroquinone;Toluhydroquinone
- CAS NO.:95-71-6
- Empirical Formula: C7H8O2
- Molecular Weight: 124.14
- MDL number: MFCD00002345
- EINECS: 202-443-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-04 13:44:46
What is 2-Methylhydroquinone?
Chemical properties
white solid
The Uses of 2-Methylhydroquinone
Antioxidant, polymerization inhibitor.
The Uses of 2-Methylhydroquinone
Methylhydroquinone is used as stabilizer and antioxidant in aerylic monomers to prevent polymerization.
The Uses of 2-Methylhydroquinone
Methylhydroquinone is a marine fungus metabolite, showing activity as an angiosupressor that interferes with the Akt pathway. Allows for screening of novel inhibitors of angiogenesis.
Definition
ChEBI: A member of the class of hydroquinones that is hydroquinone in which one of the benzene hydrogens has been replaced by a methyl group.
Synthesis Reference(s)
Tetrahedron, 44, p. 1227, 1988 DOI: 10.1016/S0040-4020(01)85902-0
Tetrahedron Letters, 22, p. 2337, 1981 DOI: 10.1016/S0040-4039(01)82900-2
General Description
Methylhydroquinone is produced by the oxidation of o-cresol by the mutants G103S, G103S/A107G, and G103S/A107T.
Flammability and Explosibility
Not classified
Biochem/physiol Actions
Methylhydroquinone (Toluquinol) inhibits the growth of endothelial and tumor cells in culture in the micromolar range and is a promising drug candidate in the treatment of cancer and other angiogenesis-related pathologies.
Purification Methods
Crystallise the quinone from EtOH. [Beilstein 6 IV 5866.]
Properties of 2-Methylhydroquinone
Melting point: | 128-130 °C(lit.) |
Boiling point: | 285°C |
Density | 1.1006 (rough estimate) |
vapor pressure | 0.004Pa at 25℃ |
refractive index | 1.4922 (estimate) |
Flash point: | 172 °C |
storage temp. | Store below +30°C. |
solubility | 77g/l |
form | Crystalline Powder |
pka | pK1:10.03;pK2:11.62 (25°C) |
color | Grayish-white to light beige |
Water Solubility | 77 g/L (25 ºC) |
BRN | 2041489 |
Stability: | Stable. Combustible. Incompatible with oxidizing agents, strong bases. |
CAS DataBase Reference | 95-71-6(CAS DataBase Reference) |
NIST Chemistry Reference | 1,4-Benzenediol, 2-methyl-(95-71-6) |
EPA Substance Registry System | 2-Methylhydroquinone (95-71-6) |
Safety information for 2-Methylhydroquinone
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral H312:Acute toxicity,dermal H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 2-Methylhydroquinone
InChIKey | CNHDIAIOKMXOLK-UHFFFAOYSA-N |
Abamectin manufacturer
Gajanan Enterprises
New Products
ALUMINIUM IODIDE 100 GM BUFFER CAPSULE PH 7.0 - 10 CAP BUFFER SOLUTION PH 9.5 (BORATE) EZEE BLUE GEL STAINER BORAX CARMINE (GRENACHERS ALCOHOLIC) POTASSIUM IODATE - IODIDE SOLN 0.1 N Dabigatran Acyl-O3-D-Glucuronide Trifluoroacetic Acid Salt Isofolic Acid Dabigatran 2-O-acylglucuronide metabolite Dabigatran Acyl-?-D- glucuronide Trifluroacetic Acid Erythromycin EP Impurity A Desloratidine Related Compound ARelated products of tetrahydrofuran
You may like
-
95-71-6 Methyl Hydroquinone 98%View Details
95-71-6 -
Methylhydroquinone, 99% CAS 95-71-6View Details
95-71-6 -
Methylhydroquinone 95% CAS 95-71-6View Details
95-71-6 -
Methylhydroquinone CAS 95-71-6View Details
95-71-6 -
Methylhydroquinone CAS 95-71-6View Details
95-71-6 -
Edoxaban Impurity 57View Details
2089454-69-1 -
Empagliflozin Bromo ImpurityView Details
-
Ipratropium EP Impurity BView Details
58073-59-9