2-Methylcyclopentanone

CAS NO.：1120-72-5
Empirical Formula: C6H10O
Molecular Weight: 98.14
MDL number: MFCD00001414
EINECS: 214-318-4
SAFETY DATA SHEET (SDS)
Update Date: 2024-07-14 20:44:35

What is 2-Methylcyclopentanone?

Chemical properties

CLEAR COLOURLESS TO VERY SLIGHTLY YELLOW LIQUID

The Uses of 2-Methylcyclopentanone

2-Methylcyclopentanone is a useful synthetic intermediate. It was used in the synthesis of MK-0354, a partial agonist of nicotinic acid and G-protein-coupled receptor 109a. It can also be used to prepare Falcipain inhibitors.

Synthesis Reference(s)

Journal of the American Chemical Society, 102, p. 190, 1980 DOI: 10.1021/ja00521a031
The Journal of Organic Chemistry, 38, p. 304, 1973 DOI: 10.1021/jo00942a022
Synthetic Communications, 8, p. 563, 1978 DOI: 10.1080/00397917808063587

Properties of 2-Methylcyclopentanone

Melting point:	-75°C
Boiling point:	139 °C (lit.)
Density	0.917 g/mL at 25 °C (lit.)
refractive index	n20/D 1.435(lit.)
Flash point:	79 °F
storage temp.	Inert atmosphere,2-8°C
form	Liquid
color	Clear colorless to very slightly yellow
Water Solubility	soluble
CAS DataBase Reference	1120-72-5(CAS DataBase Reference)
NIST Chemistry Reference	Cyclopentanone, 2-methyl-(1120-72-5)
EPA Substance Registry System	2-Methylcyclopentanone (1120-72-5)

Safety information for 2-Methylcyclopentanone

Signal word	Warning
Pictogram(s)	Flame Flammables GHS02
GHS Hazard Statements	H226:Flammable liquids
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P241:Use explosion-proof electrical/ventilating/lighting/…/equipment. P242:Use only non-sparking tools. P243:Take precautionary measures against static discharge.